LAMC2

Name	laminin subunit gamma 2
Structure	No pdb structure
Novel Interactors	1 novel interactors: SCAP
Interactors	7 interactors: BMP1 COL7A1 CSF1R FBLN2 LAMB3 NID1 SLA2
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-2 Complex Extracellular Space Cell Cortex Extracellular Matrix Perinuclear Region Of Cytoplasm
	Molecular Function	Extracellular Matrix Structural Constituent Heparin Binding
	Biological Process	Cell Adhesion Positive Regulation Of Cell Population Proliferation Epidermis Development Positive Regulation Of Cell Migration
Pathways	Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions Type I hemidesmosome assembly MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Diseases	Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS	Acne (severe) ( 30542056 ) Blood protein levels ( 30072576 ) Clozapine-induced agranulocytosis ( 25187353 ) HDL cholesterol ( 21347282 ) Low density lipoprotein cholesterol levels ( 32154731 ) Morning person ( 30696823 ) Systemic lupus erythematosus ( 21408207 )
Entrez ID	3918
HPRD ID	01031
Ensembl ID	ENSG00000058085
Uniprot IDs	Q13753
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Extracellular Matrix Basement Membrane Extracellular Matrix Structural Constituent Extracellular Matrix Binding Endodermal Cell Differentiation Collagen Type VII Trimer SREBP-SCAP Complex CSF1-CSF1R Complex Macrophage Colony-stimulating Factor Receptor Activity Response To Vitamin B3 Extracellular Region