NECAP1

Name	NECAP endocytosis associated 1
Structure
Interactors	10 interactors: AMPH AP1B1 APP DAB2 DAPK1 DNAJC5 HIP1 REL SNAP91 SNCA
GO Annotations	Cellular Component	Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Presynapse
	Molecular Function	Protein Binding
	Biological Process	Endocytosis Protein Transport Vesicle-mediated Transport Presynaptic Endocytosis
Pathways	Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
GWAS	No GWAS studies recorded
Entrez ID	25977
HPRD ID	14819
Ensembl ID	ENSG00000089818
Uniprot IDs	Q8NC96
PDB IDs	6RH5 6RH6
GO Terms Enriched among Interactors ?	Synaptic Vesicle Vesicle-mediated Transport Endocytosis Regulation Of Vesicle-mediated Transport Clathrin Coat Assembly Phospholipid Binding Import Into Cell Regulation Of Receptor-mediated Endocytosis Regulation Of Endocytosis Clathrin Binding Clathrin-coated Vesicle Membrane Positive Regulation Of Endocytosis Cytoplasmic Vesicle Apoptotic Process Positive Regulation Of Receptor-mediated Endocytosis Programmed Cell Death Cell Death Regulation Of Transport Presynapse Clathrin-coated Pit Clathrin-coated Vesicle Vesicle-mediated Transport In Synapse Clathrin Adaptor Activity Regulation Of Clathrin-dependent Endocytosis Regulation Of Apoptotic Process Synaptic Vesicle Membrane Regulation Of Neurotransmitter Uptake Regulation Of Programmed Cell Death Cellular Response To Copper Ion Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Low-density Lipoprotein Particle Receptor Binding Regulation Of Presynapse Assembly Positive Regulation Of Small Molecule Metabolic Process Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Receptor-mediated Endocytosis Amyloid Fibril Formation Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Synaptic Vesicle Exocytosis Response To Copper Ion Response To Cytokine Positive Regulation Of Catabolic Process Response To Peptide Synaptic Vesicle Endocytosis Postsynapse Presynaptic Endocytosis Regulation Of Neuron Apoptotic Process Protein-containing Complex Assembly Actin Cytoskeleton