ACIN1

Name	apoptotic chromatin condensation inducer 1
Structure
Interactors	13 interactors: ABCF3 AKR1C3 BTBD10 CASP3 CSNK2A1 KLHL26 LINC01554 PAFAH1B2 PCBD1 RNF10 SRPK2 SUMO2 YWHAG
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Nuclear Speck Nuclear Lumen Exon-exon Junction Complex ASAP Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding ATP Hydrolysis Activity Enzyme Binding
	Biological Process	MRNA Processing Apoptotic Process RNA Splicing Erythrocyte Differentiation Apoptotic Chromosome Condensation Positive Regulation Of Apoptotic Process Positive Regulation Of Monocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways	Apoptotic cleavage of cellular proteins mRNA Splicing - Major Pathway
GWAS	No GWAS studies recorded
Entrez ID	22985
HPRD ID	05191
Ensembl ID	ENSG00000100813
Uniprot IDs	B4DQZ7 E7EQT4 Q9UKV3 S4R3H4
PDB IDs	6G6S
GO Terms Enriched among Interactors ?	Positive Regulation Of Protein Metabolic Process Post-translational Protein Modification Positive Regulation Of Neuron Apoptotic Process Protein Catabolic Process Positive Regulation Of Metabolic Process Anterior Neural Tube Closure Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Epidermal Cell Differentiation Cellular Response To Staurosporine Regulation Of Protein Stability Keratinocyte Differentiation Execution Phase Of Apoptosis Phospholipase A2 Activator Activity Regulation Of Macroautophagy Regulation Of Autophagy Catabolic Process Regulation Of Translational Initiation Protein Localization To Vacuole Positive Regulation Of Macroautophagy Protein Kinase CK2 Complex Negative Regulation Of Translational Initiation Symbiont-mediated Disruption Of Host Cell PML Body PML Body Platelet-activating Factor Acetyltransferase Activity 1-alkyl-2-acetylglycerophosphocholine Esterase Complex 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tyrosine Biosynthetic Process Phenylalanine 4-monooxygenase Activity Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Presynapse Nuclear Speck Organization Protein Kinase C Inhibitor Activity Ketosteroid Monooxygenase Activity Polyprenol Catabolic Process Negative Regulation Of Retinoic Acid Biosynthetic Process Delta4-3-oxosteroid 5beta-reductase Activity Geranylgeranyl Reductase Activity 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity Ketoreductase Activity Prostaglandin D2 11-ketoreductase Activity Prostaglandin H2 Endoperoxidase Reductase Activity Prostaglandin F Synthase Activity Farnesol Catabolic Process Cellular Response To Jasmonic Acid Stimulus Regulation Of Isoprenoid Metabolic Process Sesquiterpenoid Metabolic Process Luteolysis Glial Cell Apoptotic Process Positive Regulation Of Aggrephagy 5-alpha-androstane-3-beta,17-beta-diol Dehydrogenase (NADP+) Activity