SYT9

Name	synaptotagmin 9
Structure	No pdb structure
Interactors	10 interactors: CSNK1A1 DNAJC5 NRXN1 SNAP25 SYNCRIP TMBIM6 TMEM50A TRPV1 TUBB UPK1B
GO Annotations	Cellular Component	Plasma Membrane Membrane Clathrin-coated Endocytic Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Synapse Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	SNARE Binding Phosphatidylserine Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Identical Protein Binding Metal Ion Binding Calcium Ion Sensor Activity
	Biological Process	Chemical Synaptic Transmission Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Vesicle Fusion Calcium-dependent Activation Of Synaptic Vesicle Fusion
Pathways	Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
GWAS	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134 ) Breast cancer and/or colorectal cancer ( 29698419 ) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321 ) Chagas cardiomyopathy in Tripanosoma cruzi seropositivity ( 24324551 ) Dietary fat liking ( 32516399 ) Familial lung cancer ( 29924316 ) Lead levels ( 26025379 ) Malaria ( 31844061 ) Phospholipid levels (plasma) ( 22359512 ) QRS duration in Tripanosoma cruzi seropositivity ( 24324551 )
Entrez ID	143425
HPRD ID	11618
Ensembl ID	ENSG00000170743
Uniprot IDs	Q86SS6
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Secretion Signal Release Synaptic Vesicle Exocytosis Neurotransmitter Secretion Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Temperature-gated Ion Channel Activity Response To Capsazepine Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation Membrane Secretion By Cell Neurotransmitter Transport Regulated Exocytosis Calcium-dependent Protein Binding Vesicle-mediated Transport In Synapse Specific Granule Membrane Establishment Of Localization In Cell Calcium Channel Activity Endoribonuclease Inhibitor Activity Apical Plasma Membrane Urothelial Plaque Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Fever Generation Smooth Muscle Contraction Involved In Micturition GABA-ergic Synapse Protein Complex Involved In Cell-cell Adhesion Guanylate Kinase-associated Protein Clustering Neuromuscular Junction Positive Regulation Of Neuromuscular Synaptic Transmission Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Protein-containing Complex Assembly Synaptic Vesicle Ribbon Synapse Vesicle Monoatomic Cation Transmembrane Transport Dense Core Granule Exocytosis Metal Ion Transport Inorganic Cation Transmembrane Transport Presynaptic Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Positive Regulation Of Synaptic Transmission Vesicle Localization Learning Presynaptic Dense Core Vesicle Exocytosis Neuronal Dense Core Vesicle Exocytosis Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response Structural Molecule Activity