| ACTG1 and APOE |
actin gamma 1 |
apolipoprotein E |
- Axon guidance
- Gap junction degradation
- Adherens junctions interactions
- Translocation of GLUT4 to the plasma membrane
- L1CAM interactions
- Recycling pathway of L1
- VEGFA-VEGFR2 Pathway
- EPHB-mediated forward signaling
- Interaction between L1 and Ankyrins
- Cell-cell junction organization
- EPH-ephrin mediated repulsion of cells
- Gap junction trafficking and regulation
- EPH-Ephrin signaling
- Fcgamma receptor (FCGR) dependent phagocytosis
- Regulation of actin dynamics for phagocytic cup formation
- Innate Immune System
- Cell junction organization
- Formation of annular gap junctions
- Gap junction trafficking
- Signaling by VEGF
- Cell-extracellular matrix interactions
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- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
| ACTN1 and PSEN1 |
actinin, alpha 1 |
presenilin 1 |
- Cell junction organization
- Syndecan interactions
- Response to elevated platelet cytosolic Ca2+
- Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
- Nephrin interactions
- Platelet degranulation
- Non-integrin membrane-ECM interactions
- Platelet activation, signaling and aggregation
- Cell-extracellular matrix interactions
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- Degradation of the extracellular matrix
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|
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| ALB and APOE |
albumin |
apolipoprotein E |
- Lipoprotein metabolism
- Bile acid and bile salt metabolism
- Metabolism of lipids and lipoproteins
- Recycling of bile acids and salts
- Platelet degranulation
- Lipid digestion, mobilization, and transport
- Transport of organic anions
- SLC-mediated transmembrane transport
- HDL-mediated lipid transport
- Scavenging of heme from plasma
- Response to elevated platelet cytosolic Ca2+
- Platelet activation, signaling and aggregation
- Transport of vitamins, nucleosides, and related molecules
|
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
| APBA1 and PSEN1 |
amyloid beta (A4) precursor protein-binding, family A, member 1 |
presenilin 1 |
|
- Degradation of the extracellular matrix
|
|
|
|
|
| APOE and TYRO3 |
apolipoprotein E |
TYRO3 protein tyrosine kinase |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
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| APOE and RNF32 |
apolipoprotein E |
ring finger protein 32 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and CDC37 |
apolipoprotein E |
cell division cycle 37 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
- Signaling by ERBB2
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- Signaling by EGFR in Cancer
- Signaling by Ligand-Responsive EGFR Variants in Cancer
- Signaling by EGFRvIII in Cancer
- Constitutive Signaling by EGFRvIII
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and NEFM |
apolipoprotein E |
neurofilament, medium polypeptide |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
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- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and RPL4 |
apolipoprotein E |
ribosomal protein L4 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
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- Nonsense-Mediated Decay (NMD)
- Translation
- SRP-dependent cotranslational protein targeting to membrane
- Eukaryotic Translation Termination
- Peptide chain elongation
- Influenza Infection
- Viral mRNA Translation
- L13a-mediated translational silencing of Ceruloplasmin expression
- Influenza Life Cycle
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
- Influenza Viral RNA Transcription and Replication
- GTP hydrolysis and joining of the 60S ribosomal subunit
- Eukaryotic Translation Initiation
- Formation of a pool of free 40S subunits
- Eukaryotic Translation Elongation
- Cap-dependent Translation Initiation
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and PRAM1 |
apolipoprotein E |
PML-RARA regulated adaptor molecule 1 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and VLDLR |
apolipoprotein E |
very low density lipoprotein receptor |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and IQSEC1 |
apolipoprotein E |
IQ motif and Sec7 domain 1 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and FARSA |
apolipoprotein E |
phenylalanyl-tRNA synthetase, alpha subunit |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
- Cytosolic tRNA aminoacylation
- tRNA Aminoacylation
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and CYP2C8 |
apolipoprotein E |
cytochrome P450, family 2, subfamily C, polypeptide 8 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
- Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)
- Metabolism of lipids and lipoproteins
- Metabolic disorders of biological oxidation enzymes
- Phase 1 - Functionalization of compounds
- Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
- Arachidonic acid metabolism
- Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)
- Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)
- Cytochrome P450 - arranged by substrate type
- CYP2E1 reactions
- Biological oxidations
- Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)
- Defective FMO3 causes Trimethylaminuria (TMAU)
- Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
- Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
- Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)
- Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)
- Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)
- Defective CYP1B1 causes Glaucoma
- Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)
- Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)
- Defective CYP19A1 causes Aromatase excess syndrome (AEXS)
- Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
- Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)
- Xenobiotics
- Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
- Defective MAOA causes Brunner syndrome (BRUNS)
- Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)
- Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and CYP2C18 |
apolipoprotein E |
cytochrome P450, family 2, subfamily C, polypeptide 18 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
- Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)
- Defective FMO3 causes Trimethylaminuria (TMAU)
- Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)
- Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
- Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)
- Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)
- Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)
- Metabolic disorders of biological oxidation enzymes
- Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
- Phase 1 - Functionalization of compounds
- Defective CYP1B1 causes Glaucoma
- Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)
- Defective CYP19A1 causes Aromatase excess syndrome (AEXS)
- Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)
- Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
- Xenobiotics
- Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)
- Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)
- Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)
- Cytochrome P450 - arranged by substrate type
- Defective MAOA causes Brunner syndrome (BRUNS)
- Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)
- Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)
- Biological oxidations
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and MID1IP1 |
apolipoprotein E |
MID1 interacting protein 1 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and MAP2 |
apolipoprotein E |
microtubule-associated protein 2 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
- Estramustine
- Paclitaxel
- Docetaxel
|
|
|
| APOE and CSNK2A1 |
apolipoprotein E |
casein kinase 2, alpha 1 polypeptide |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
- Mitotic Prometaphase
- Signal transduction by L1
- Axon guidance
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- L1CAM interactions
- Signaling by Wnt
- Cell Cycle, Mitotic
- M Phase
- WNT mediated activation of DVL
- TCF dependent signaling in response to WNT
- RNF mutants show enhanced WNT signaling and proliferation
- XAV939 inhibits tankyrase, stabilizing AXIN
- Signaling by WNT in cancer
- Condensation of Prometaphase Chromosomes
|
- Human Serum Albumin
- Serum albumin iodonated
|
- (5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid
- 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
- Resveratrol
- 1,8-Di-Hydroxy-4-Nitro-Anthraquinone
- Benzamidine
- 5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone
- Phosphoaminophosphonic Acid-Adenylate Ester
- Tetrabromo-2-Benzotriazole
- DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE
- S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE
- 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE
- 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one
- N,N\'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE
- 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE
- 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione
- 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole
- 1,2,5,8-tetrahydroxyanthracene-9,10-dione
- Ellagic Acid
|
|
|
| APOE and SCARB1 |
apolipoprotein E |
scavenger receptor class B, member 1 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|
| APOE and ARFGAP1 |
apolipoprotein E |
ADP-ribosylation factor GTPase activating protein 1 |
- Lipoprotein metabolism
- Metabolism of lipids and lipoproteins
- Chylomicron-mediated lipid transport
- Lipid digestion, mobilization, and transport
- Diseases associated with visual transduction
- HDL-mediated lipid transport
- Visual phototransduction
- Scavenging by Class A Receptors
- Retinoid metabolism and transport
|
- IRE1alpha activates chaperones
- COPI Mediated Transport
- XBP1(S) activates chaperone genes
- Golgi to ER Retrograde Transport
- Unfolded Protein Response (UPR)
|
- Human Serum Albumin
- Serum albumin iodonated
|
|
|
|