NR1D2 and RGN

Number of citations of the paper that reports this interaction (PubMedID 15604093)
0

Data Source:
HPRD (two hybrid)

		NR1D2	RGN
Description		nuclear receptor subfamily 1 group D member 2	regucalcin
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Gluconolactonase Activity Calcium Ion Binding Zinc Ion Binding Hydrolase Activity Enzyme Regulator Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Regulation Of Circadian Rhythm Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation	Intracellular Calcium Ion Homeostasis Positive Regulation Of ATP-dependent Activity Regulation Of Calcium-mediated Signaling
Pathways		Nuclear Receptor transcription pathway
Drugs		SR-9009 SR-9011	Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Parkinson's disease progression (cognitive) ( 33111402) Refractive error ( 32231278)
Interacting Genes		54 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 CYSRT1 DELEC1 EFEMP2 GTF2B HDAC1 HOXA1 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LGALS8 MEOX2 MID2 MYLIP MYO15B NBPF19 NCOA5 NCOR1 NOTCH2NLA NR1D1 PCSK5 PRMT6 PROP1 RBPMS RGN RORC SIN3B TAF6 TAF9 TBC1D21 TENT5B TRIM27 TRIM55 TRIM63 TRIP6 TTC3 UBE2I ZNF587	2 interacting genes: NR1D2 THRA
Entrez ID		9975	9104
HPRD ID		03809	02196
Ensembl ID		ENSG00000174738	ENSG00000130988
Uniprot IDs		B4DXD3 F1D8P2 Q14995	Q15493 V9HWF8
PDB IDs		2V0V 2V7C 3CQV 4N73 6WMQ 6WMS	3G4E 3G4H 4GNB 4GNC
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Circadian Regulation Of Gene Expression Circadian Rhythm Negative Regulation Of Catabolic Process Nuclear Thyroid Hormone Receptor Binding Rhythmic Process Transcription Factor TFIID Complex Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway RNA Polymerase II General Transcription Initiation Factor Activity Regulation Of Circadian Rhythm RNA Polymerase II Preinitiation Complex Assembly Cytosol	Nuclear Receptor Activity Regulation Of Lipid Metabolic Process Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Thyroid Hormone Receptor Signaling Pathway Female Courtship Behavior Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Hormone-mediated Signaling Pathway Positive Regulation Of Female Receptivity Sequence-specific DNA Binding Regulation Of Thyroid Hormone Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Initiation Thyroid Hormone Binding Negative Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Female Receptivity Female Mating Behavior Type I Pneumocyte Differentiation General Transcription Initiation Factor Binding DNA-binding Transcription Factor Activity Cell Aggregation Cartilage Condensation Mating Behavior Retinoic Acid Receptor Signaling Pathway Circadian Behavior Regulation Of Skeletal Muscle Cell Differentiation Rhythmic Behavior Lung Epithelial Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase II TBP-class Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Lung Cell Differentiation Thyroid Gland Development Regulation Of Myeloid Cell Apoptotic Process Reproductive Behavior Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Response To Cold Positive Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process MRNA Transcription Regulation Of Lipid Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Energy Homeostasis Erythrocyte Differentiation Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Initiation
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