NR1D2 and NCOA5

Number of citations of the paper that reports this interaction (PMID 11113208)
12

Data Source:
HPRD (in vitro, two hybrid)

		NR1D2	NCOA5
Gene Name		nuclear receptor subfamily 1, group D, member 2	nuclear receptor coactivator 5
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Nucleus Nucleoplasm Actin Cytoskeleton
	Molecular Function	Core Promoter Sequence-specific DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding	Chromatin Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Regulation Of Lipid Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Rhythmic Process Regulation Of Inflammatory Response Lipid Homeostasis Regulation Of Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Multiple sclerosis ( 21833088)
Protein-Protein Interactions		19 interactors: CUL1 GTF2B HDAC1 KRT40 KRTAP10-9 KRTAP4-2 MID2 NCOA5 NCOR1 NOTCH2NL NR1D1 PRMT6 RBPMS RGN SIN3B TAF6 TAF9 TRIM27 UBE2I	8 interactors: CDC37 HTATIP2 KHDRBS2 KHDRBS3 NR1D2 SYT16 TSC22D1 WDYHV1
Entrez ID		9975	57727
HPRD ID		03809	14813
Ensembl ID		ENSG00000174738	ENSG00000124160
Uniprot IDs		B4DXD3 F1D8P2 Q14995 Q6NSM0	Q9HCD5
PDB IDs		2V0V 2V7C 3CQV	1V95 2J7X 2J7Y
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription, DNA-templated RNA Biosynthetic Process Viral Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Viral Transcription Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Notch Signaling Pathway Negative Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Circadian Rhythm Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Negative Regulation Of Viral Process Regulation Of Cellular Process Circadian Regulation Of Gene Expression Regulation Of Signal Transduction Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Elongation Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Modification Rhythmic Process Negative Regulation Of Viral Release From Host Cell Regulation Of Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Nitrogen Compound Metabolic Process Regulation Of Receptor Biosynthetic Process Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Viral Release From Host Cell Histone Modification
Tagcloud ?		adopting af2 arrangement bend bulky cavity circadian clock closing cognate conformation dimeric erb erbalpha erbbeta filled filling flexibility geometry h11 helix hydrophobic kinked lbp orphan pocket putative rev stabilize
Tagcloud (Difference) ?		adopting af2 arrangement bend bulky cavity circadian clock closing cognate conformation dimeric erb erbalpha erbbeta filled filling flexibility geometry h11 helix hydrophobic kinked lbp orphan pocket putative rev stabilize
Tagcloud (Intersection) ?