RGN and NR1D2

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
HPRD (two hybrid)

		RGN	NR1D2
Gene Name		regucalcin	nuclear receptor subfamily 1, group D, member 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Gluconolactonase Activity Calcium Ion Binding Zinc Ion Binding Enzyme Regulator Activity	Core Promoter Sequence-specific DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding
	Biological Process	Cellular Calcium Ion Homeostasis L-ascorbic Acid Biosynthetic Process Positive Regulation Of ATPase Activity Regulation Of Calcium-mediated Signaling	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Regulation Of Lipid Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Rhythmic Process Regulation Of Inflammatory Response Lipid Homeostasis Regulation Of Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation
Pathways			Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: NR1D2 THRA	19 interactors: CUL1 GTF2B HDAC1 KRT40 KRTAP10-9 KRTAP4-2 MID2 NCOA5 NCOR1 NOTCH2NL NR1D1 PRMT6 RBPMS RGN SIN3B TAF6 TAF9 TRIM27 UBE2I
Entrez ID		9104	9975
HPRD ID		02196	03809
Ensembl ID		ENSG00000130988	ENSG00000174738
Uniprot IDs		Q15493	B4DXD3 F1D8P2 Q14995 Q6NSM0
PDB IDs		3G4E 3G4H 4GNB 4GNC	2V0V 2V7C 3CQV
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Regulation Of Lipid Metabolic Process Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Female Receptivity Cellular Response To Organic Cyclic Compound Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Lipid Response To Steroid Hormone Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Cellular Response To Hormone Stimulus Female Courtship Behavior Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Energy Homeostasis Regulation Of Female Receptivity Female Mating Behavior Response To Lipid Type I Pneumocyte Differentiation Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Regulation Of Skeletal Muscle Cell Differentiation Cytoplasmic Sequestering Of Transcription Factor Response To Hormone Cytoplasmic Sequestering Of Protein Cartilage Condensation Regulation Of DNA-templated Transcription, Initiation Thyroid Gland Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Myotube Differentiation Mating Behavior Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Homeostatic Process Negative Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Mating Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Response To Cold Regulation Of Lipid Catabolic Process Positive Regulation Of Cellular Biosynthetic Process	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription, DNA-templated RNA Biosynthetic Process Viral Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Viral Transcription Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Notch Signaling Pathway Negative Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Circadian Rhythm Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Negative Regulation Of Viral Process Regulation Of Cellular Process Circadian Regulation Of Gene Expression Regulation Of Signal Transduction Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Elongation Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Modification Rhythmic Process Negative Regulation Of Viral Release From Host Cell Regulation Of Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Nitrogen Compound Metabolic Process Regulation Of Receptor Biosynthetic Process Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Viral Release From Host Cell Histone Modification
Tagcloud ?		actinomycin antiapoptotic counterparts diminished enzymatic ex fertility germ herein inducers modulating mug noxious oncological overexpressing preservation proapoptotic protects regucalcin seminiferous set situations suppresses testicular testis tg thap thapsigargin tubules	adopting af2 arrangement bend bulky cavity circadian clock closing cognate conformation dimeric erb erbalpha erbbeta filled filling flexibility geometry h11 helix hydrophobic kinked lbp orphan pocket putative rev stabilize
Tagcloud (Difference) ?		actinomycin antiapoptotic counterparts diminished enzymatic ex fertility germ herein inducers modulating mug noxious oncological overexpressing preservation proapoptotic protects regucalcin seminiferous set situations suppresses testicular testis tg thap thapsigargin tubules	adopting af2 arrangement bend bulky cavity circadian clock closing cognate conformation dimeric erb erbalpha erbbeta filled filling flexibility geometry h11 helix hydrophobic kinked lbp orphan pocket putative rev stabilize
Tagcloud (Intersection) ?