KIF14 and TUBGCP2

Number of citations of the paper that reports this interaction (PubMedID 25348260)
69

Data Source:
BioGRID (unspecified method)

		KIF14	TUBGCP2
Description		kinesin family member 14	tubulin gamma complex component 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Plasma Membrane Membrane Midbody Spindle Midzone Flemming Body	Spindle Pole Gamma-tubulin Complex Nucleoplasm Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Cytoplasmic Microtubule Membrane Ciliary Basal Body
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Tubulin Binding ATP Hydrolysis Activity Protein Kinase Binding PDZ Domain Binding	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Regulation Of Cell Growth Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Chromosome Alignment Positive Regulation Of Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Cerebellar Granular Layer Structural Organization Cerebellar Purkinje Cell Layer Structural Organization Cerebellar Cortex Development Hippocampus Development Olfactory Bulb Development Cell Proliferation In Forebrain Cerebral Cortex Development Regulation Of Cell Adhesion Regulation Of Cell Migration SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Myelination Activation Of Protein Kinase Activity Positive Regulation Of Cytokinesis Regulation Of Rap Protein Signal Transduction Negative Regulation Of Integrin Activation Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Establishment Of Protein Localization Cell Division Regulation Of Cell Maturation Regulation Of G1/S Transition Of Mitotic Cell Cycle	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration Microtubule Nucleation Brain Development Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		RHO GTPases activate CIT RND2 GTPase cycle RND1 GTPase cycle	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Neurofibrillary tangles ( 31497858) Refractive error ( 32231278) Tandem gait ( 26219847)	Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)
Interacting Genes		3 interacting genes: CLK1 TUBG1 TUBGCP2	4 interacting genes: CEBPA KIF14 PCNT UBC
Entrez ID		9928	10844
HPRD ID		06605	18245
Ensembl ID		ENSG00000118193	ENSG00000130640
Uniprot IDs		A0A384P5W4 Q15058	Q53EQ3 Q9BSJ2
PDB IDs			6V6B 6V6S 6X0V 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 8Q62 8RX1 8VRD 8VRJ 8VRK 9H9P
Enriched GO Terms of Interacting Partners?		Gamma-tubulin Complex Microtubule Nucleation Cytoplasmic Microtubule Organization Cytoplasmic Microtubule Mitotic Cell Cycle Spindle Organization Microtubule Nucleator Activity Polar Microtubule Ciliary Basal Body Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Organization Supramolecular Fiber Organization Microtubule Minus-end Binding Mitotic Spindle Microtubule Meiotic Spindle Organization Centrosome Pericentriolar Material Protein Serine/threonine/tyrosine Kinase Activity Non-motile Cilium Mitotic Sister Chromatid Segregation Microtubule-based Process Gamma-tubulin Binding Non-membrane Spanning Protein Tyrosine Kinase Activity Spindle Microtubule Sister Chromatid Segregation Condensed Nuclear Chromosome Nuclear Chromosome Segregation Cytoskeleton Organization Cell Leading Edge Apical Part Of Cell Structural Constituent Of Cytoskeleton Reproductive Process Mitotic Spindle Organization Microtubule Organizing Center Spindle Assembly
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