SMC4 and NCAPD2

Number of citations of the paper that reports this interaction (PMID 10958694)
34

Data Source:
HPRD (in vivo)

		SMC4	NCAPD2
Gene Name		structural maintenance of chromosomes 4	non-SMC condensin I complex, subunit D2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensin Complex Nucleus Nucleoplasm Cytoplasm Cytosol	Nuclear Chromosome Condensed Chromosome Condensin Complex Condensin Core Heterodimer Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Pronucleus
	Molecular Function	Protein Binding ATP Binding Protein Heterodimerization Activity	Protein Binding Histone Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization	Mitotic Cell Cycle Mitotic Chromosome Condensation Cell Division
Pathways		Mitotic Prometaphase Mitotic Prophase Condensation of Prophase Chromosomes Cell Cycle, Mitotic M Phase Condensation of Prometaphase Chromosomes	Mitotic Prometaphase Cell Cycle, Mitotic M Phase Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: NCAPD2 SMC2 TRAF3IP1	5 interactors: CDK1 CSNK2A1 NCAPH SMC2 SMC4
Entrez ID		10051	9918
HPRD ID		09276	06472
Ensembl ID		ENSG00000113810	ENSG00000010292
Uniprot IDs		E9PD53 Q9NTJ3	B3KMS0 B3KY03 F5GZJ1 Q15021
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Chromosome Condensation Chromosome Condensation Mitotic Sister Chromatid Segregation Sister Chromatid Segregation DNA Packaging Chromosome Segregation DNA Conformation Change Mitotic Nuclear Division Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Cell Division Meiotic Chromosome Condensation Negative Regulation Of Interferon-beta Production Mitotic Cell Cycle Process Organelle Organization Post-anal Tail Morphogenesis Mitotic Cell Cycle Negative Regulation Of Defense Response To Virus Kinetochore Organization Negative Regulation Of Embryonic Development Negative Regulation Of Smoothened Signaling Pathway Intraciliary Transport Regulation Of Interferon-beta Production Chromosome Organization Cell Cycle Process Negative Regulation Of Type I Interferon Production DNA Metabolic Process Embryonic Camera-type Eye Development Neural Tube Patterning Embryonic Digit Morphogenesis Cell Cycle Meiotic Chromosome Segregation Regulation Of Defense Response To Virus Embryonic Heart Tube Development Regulation Of Smoothened Signaling Pathway Regulation Of Type I Interferon Production Regulation Of Embryonic Development Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport	Chromosome Condensation Mitotic Chromosome Condensation DNA Packaging Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Conformation Change Meiotic Chromosome Condensation Mitotic Nuclear Division Cell Cycle Process Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Cell Division Cell Cycle Chromosome Segregation Kinetochore Organization Chromosome Organization DNA Metabolic Process Meiotic Chromosome Segregation Pronuclear Fusion Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Checkpoint Meiotic Nuclear Division Nitrogen Compound Metabolic Process Meiotic Cell Cycle Reproduction Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Growth Cell Cycle Checkpoint Regulation Of Schwann Cell Differentiation Organelle Organization Protein Localization To Kinetochore Protein Localization To Chromosome, Centromeric Region Positive Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Protein Catabolic Process Axon Guidance Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Regulation Of Protein Import Into Nucleus, Translocation Mitotic G2 DNA Damage Checkpoint Ventricular Cardiac Muscle Cell Development Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Response To Copper Ion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis
Tagcloud ?		affymetrix annotations apdf aurka bicarbonate blpdf bpdf buffered ccnb1 ccne2 cdk1 containingpdf cpdf diamond diluted genechip icodextrin insufficiently ipdf kif11 kif14 lpdf mesothelial omentum pdf pmc repressors u133plus2 uremic	aberration birc5 bub1 candidates cysts datasets defining driver dysregulated epcam epithelium estrous fallopian hormones inclusion list nuak2 ovarian ovulation ovulations ovulatory prioritised proestrus publically represented segregation serous silico tube
Tagcloud (Difference) ?		affymetrix annotations apdf aurka bicarbonate blpdf bpdf buffered ccnb1 ccne2 cdk1 containingpdf cpdf diamond diluted genechip icodextrin insufficiently ipdf kif11 kif14 lpdf mesothelial omentum pdf pmc repressors u133plus2 uremic	aberration birc5 bub1 candidates cysts datasets defining driver dysregulated epcam epithelium estrous fallopian hormones inclusion list nuak2 ovarian ovulation ovulations ovulatory prioritised proestrus publically represented segregation serous silico tube
Tagcloud (Intersection) ?