SUPT7L and SERTAD2

Number of citations of the paper that reports this interaction (PMID 17141982)
4

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SUPT7L	SERTAD2
Gene Name		suppressor of Ty 7 (S. cerevisiae)-like	SERTA domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus STAGA Complex	Nucleus Cytoplasm
	Molecular Function	Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding	Transcription Coactivator Activity
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Maintenance Of Protein Location In Nucleus	Transcription, DNA-templated Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Visceral fat ( 22589738)
Protein-Protein Interactions		6 interactors: CDCA4 PTN SERTAD1 SERTAD2 SUMO1 TAF10	7 interactors: CREBBP E2F1 KAT2B SUPT7L TFDP1 TRIM28 XPO1
Entrez ID		9913	9792
HPRD ID		18115	18040
Ensembl ID		ENSG00000119760	ENSG00000179833
Uniprot IDs		O94864	Q14140
PDB IDs
Enriched GO Terms of Interacting Partners?			Notch Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter N-terminal Peptidyl-lysine Acetylation DNA-templated Transcription, Initiation Peptidyl-lysine Modification Anoikis Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Intracellular Transport Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation Transcription, DNA-templated Protein Acetylation Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process N-terminal Protein Amino Acid Modification Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Localization RNA Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Transcription From RNA Polymerase II Promoter Histone H3 Acetylation Cellular Macromolecule Biosynthetic Process Peptidyl-amino Acid Modification Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Localization Positive Regulation Of Mitochondrion Organization Negative Regulation Of Transcription, DNA-templated Histone Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process
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