SERTAD2 and IGFN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SERTAD2	IGFN1
Description		SERTA domain containing 2	immunoglobulin like and fibronectin type III domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Z Disc
	Molecular Function	Transcription Coactivator Activity Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell Growth Positive Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Apolipoprotein B levels ( 32203549) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femur bone mineral density x serum urate levels interaction ( 34046847) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 29403010 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 28957414 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Visceral fat ( 22589738)	Asthma ( 29273806) Height ( 28552196)
Interacting Genes		25 interacting genes: AIRIM ATG12 CDC7 CKS1B CREBBP CTNNA3 E2F1 ESPNL HELLS IGFN1 KAT2B KAT5 PARVG PIK3R3 PLA2G6 PRKAB2 STRA8 SUPT7L TFDP1 TNS2 TRIM28 XPO1 ZNF524 ZNF581 ZSCAN22	40 interacting genes: ACTMAP BANP BLZF1 COG6 CRX DDAH2 FXR2 GOLGA2 HIVEP1 HOXA1 HOXD3 KCTD9 KIFC3 KRT39 KRTAP6-2 LHX9 LZTS2 MEOX2 MID2 MYOD1 NHLRC4 PIBF1 PNMA1 POF1B POU6F2 PRKAR1B PRR23B SERTAD2 SPAG5 TAX1BP1 TRIM21 TRIM27 TRIM35 TRIM42 TRIP13 TSC1 UBAP2 USP54 ZNF620 ZNF688
Entrez ID		9792	91156
HPRD ID		18040	16812
Ensembl ID		ENSG00000179833	ENSG00000163395
Uniprot IDs		Q14140	Q86VF2
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Binding Peptidyl-lysine Acetylation Acetyltransferase Activity Histone Acetyltransferase Complex N-terminal Peptidyl-lysine Acetylation Protein-lysine-acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Regulation Of DNA Metabolic Process Histone Acetyltransferase Activity Protein Acetylation Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Regulation Of DNA Repair Positive Regulation Of Cell Cycle Process Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Recombinational Repair Transcription Coactivator Activity Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Cell Cycle Process Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore N-terminal Protein Amino Acid Acetylation Anoikis Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Regulation Of Metaphase Plate Congression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm Double-strand Break Repair Attachment Of Mitotic Spindle Microtubules To Kinetochore Transcription Regulator Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Recombination Positive Regulation Of Lipid Biosynthetic Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore SAGA Complex Protein Kinase Binding Cellular Response To Nutrient Levels Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Phosphatidylethanolamine Metabolic Process Chromatin Binding DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Positive Regulation Of Chromosome Segregation Protein Binding	Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Regulation Of Viral Transcription Protein Binding Golgi Organization Protein Localization To Cytoskeleton Sequence-specific Double-stranded DNA Binding
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