SERTAD2 and CEP68

		SERTAD2	CEP68
Description		SERTA domain containing 2	centrosomal protein 68
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Cell Junction Centriolar Satellite Ciliary Basal Body
	Molecular Function	Transcription Coactivator Activity Protein Binding	Protein Binding Protein Kinase Binding Protein Domain Specific Binding
	Biological Process	Negative Regulation Of Cell Growth Positive Regulation Of DNA-templated Transcription	Centrosome Cycle Centriole-centriole Cohesion Protein Localization To Organelle
Pathways
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Apolipoprotein B levels ( 32203549) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femur bone mineral density x serum urate levels interaction ( 34046847) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 29403010 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 28957414 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Visceral fat ( 22589738)	Apolipoprotein A1 levels ( 32203549) Atrial fibrillation ( 33990960 28416818 28416822 30061737 29892015) HDL cholesterol levels ( 32203549) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolic syndrome ( 31589552) Platelet distribution width ( 32888494) Pulse pressure ( 30578418 28135244 27841878) Systolic blood pressure ( 30578418 27841878) Triglyceride levels ( 32203549) Triglycerides ( 30275531 25961943) Type 2 diabetes ( 30054458 29632382 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		25 interacting genes: AIRIM ATG12 CDC7 CKS1B CREBBP CTNNA3 E2F1 ESPNL HELLS IGFN1 KAT2B KAT5 PARVG PIK3R3 PLA2G6 PRKAB2 STRA8 SUPT7L TFDP1 TNS2 TRIM28 XPO1 ZNF524 ZNF581 ZSCAN22	9 interacting genes: COG2 CTBP1 CTBP2 HGS MCM7 TRAF3IP3 TRIM54 TSNAX USHBP1
Entrez ID		9792	23177
HPRD ID		18040	13808
Ensembl ID		ENSG00000179833	ENSG00000011523
Uniprot IDs		Q14140	A0A994J4E5 Q76N32
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Binding Peptidyl-lysine Acetylation Acetyltransferase Activity Histone Acetyltransferase Complex N-terminal Peptidyl-lysine Acetylation Protein-lysine-acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Regulation Of DNA Metabolic Process Histone Acetyltransferase Activity Protein Acetylation Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Regulation Of DNA Repair Positive Regulation Of Cell Cycle Process Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Recombinational Repair Transcription Coactivator Activity Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Cell Cycle Process Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore N-terminal Protein Amino Acid Acetylation Anoikis Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Regulation Of Metaphase Plate Congression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm Double-strand Break Repair Attachment Of Mitotic Spindle Microtubules To Kinetochore Transcription Regulator Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Recombination Positive Regulation Of Lipid Biosynthetic Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore SAGA Complex Protein Kinase Binding Cellular Response To Nutrient Levels Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Phosphatidylethanolamine Metabolic Process Chromatin Binding DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Positive Regulation Of Chromosome Segregation Protein Binding	White Fat Cell Differentiation Viral Genome Replication Presynaptic Endocytosis NAD Binding Transcription Coregulator Binding Transcription Corepressor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
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