ACYP2 and CREBZF

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ACYP2	CREBZF
Description		acylphosphatase 2	CREB/ATF bZIP transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Chromatin Nucleus Nucleoplasm Mitochondrion RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Acylphosphatase Activity Protein Binding Hydrolase Activity Identical Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Phosphate-containing Compound Metabolic Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Virus ATF6-mediated Unfolded Protein Response Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-binding Transcription Factor Activity Integrated Stress Response Signaling
Pathways
Drugs		Formic acid
Diseases
GWAS		Blood protein levels ( 30072576) Chronotype ( 27494321 30696823) Heel bone mineral density ( 30598549) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Leukocyte telomere length ( 31171785 32109421) Morning vs. evening chronotype ( 27494321) Refractive error ( 32231278) Sudden cardiac arrest ( 21658281) Telomere length ( 23535734)	Refractive error ( 32231278)
Interacting Genes		2 interacting genes: CREBZF SULT2B1	19 interacting genes: ACYP2 ATF4 ATF6B BTG3 CTNNBL1 DSCR9 HCFC1 HEY1 LCOR NFE2L1 NFE2L2 NRIP1 RALBP1 RSPH1 TIAM1 TP53 TTC23 XBP1 ZNF512B
Entrez ID		98	58487
HPRD ID		00028	07340
Ensembl ID		ENSG00000170634	ENSG00000137504
Uniprot IDs		A0A140VJD7 E9PF46 F8WA34 P14621 U3KQL2	E9PIM0 Q9NS37
PDB IDs
Enriched GO Terms of Interacting Partners?		Alcohol Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Steroid Hormone Binding ATF6-mediated Unfolded Protein Response Sulfation Small Molecule Binding Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Epidermis Development Sulfotransferase Activity Integrated Stress Response Signaling ER-nucleus Signaling Pathway Cholesterol Binding Regulation Of Epidermis Development Positive Regulation Of Epithelial Cell Differentiation Regulation Of Epidermal Cell Differentiation Endoplasmic Reticulum Unfolded Protein Response	ER-nucleus Signaling Pathway Cellular Response To Glucose Starvation Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Response To Endoplasmic Reticulum Stress DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Transcription Cis-regulatory Region Binding Nuclear Estrogen Receptor Binding Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulator Complex Histone Deacetylase Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleoplasm ATF6-mediated Unfolded Protein Response Response To Oxidative Stress Cellular Response To Starvation Regulation Of Intrinsic Apoptotic Signaling Pathway RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of RNA Metabolic Process PERK-mediated Unfolded Protein Response Promoter-specific Chromatin Binding Cellular Response To Oxidative Stress General Transcription Initiation Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Response To Starvation Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Nutrient Levels DNA Binding Positive Regulation Of ERAD Pathway Cellular Response To Laminar Fluid Shear Stress DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Cellular Response To Chemical Stress Negative Regulation Of Macromolecule Biosynthetic Process Intracellular Signaling Cassette Nucleus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
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