RASSF2 and KIZ

Data Source: HiPPIP (Novel)

		RASSF2	KIZ
Name		Ras association domain family member 2	kizuna centrosomal protein
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Protein-containing Complex	Cytoplasm Centrosome Cytoskeleton Cell Projection
	Molecular Function	Protein Kinase Activity Protein Binding	Protein Binding Protein Kinase Binding
	Biological Process	Skeletal System Development Ossification Signal Transduction Canonical NF-kappaB Signal Transduction Positive Regulation Of Protein Autophosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Apoptotic Process Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Bone Remodeling Homeostasis Of Number Of Cells Protein Stabilization Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Non-canonical NF-kappaB Signal Transduction	Spindle Organization
GWAS		Refractive error ( 32231278 ) Suicide attempt severity in mood disorders ( 33783297 ) Systemic lupus erythematosus ( 24871463 )	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028 ) Appendicular lean mass ( 33097823 ) Autism spectrum disorder ( 30804558 ) Height ( 31562340 )
Novel Interactors		3 novel interactors: IRAK1 KIZ NKX2-2	10 novel interactors: AAR2 ANKEF1 CDK5RAP1 EIF2S2 NKX2-2 OVOL2 PRND RASSF2 SAMHD1 SPEF1
Interacting Genes		8 interacting genes: HRAS KDM1A KRAS PRMT3 PRMT6 RASSF5 S100Z SUV39H1	4 interacting genes: CRYAA MEOX2 TACC3 TFIP11
Entrez ID		9770	55857
HPRD ID		15218	12760
Ensembl ID		ENSG00000101265	ENSG00000088970
Uniprot IDs		P50749	A0A087X251 Q2M2Z5
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Histone Methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Glial Cell Development Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine N-methyltransferase Activity Regulation Of Multicellular Organismal Process Histone H3 Methyltransferase Activity Cellular Response To Gamma Radiation Regulation Of Long-term Neuronal Synaptic Plasticity Methyltransferase Activity Protein-membrane Adaptor Activity Methylation Regulation Of Protein Ubiquitination Regulation Of Neuronal Synaptic Plasticity Response To Gamma Radiation Positive Regulation Of Gene Expression MAPK Cascade Regulation Of Cellular Senescence Positive Regulation Of Neurogenesis Positive Regulation Of Nervous System Development Ventral Spinal Cord Interneuron Fate Determination Type B Pancreatic Cell Fate Commitment Chromatin Remodeling Epigenetic Regulation Of Gene Expression Regulation Of Post-translational Protein Modification Histone H2AR3 Methyltransferase Activity Cellular Senescence Positive Regulation Of Gliogenesis Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription GDP Binding G Protein Activity Regulation Of Macromolecule Metabolic Process Cellular Response To Ionizing Radiation Regulation Of RNA Biosynthetic Process GTPase Complex Ras Protein Signal Transduction Regulation Of Multicellular Organismal Development Pancreatic A Cell Fate Commitment Pancreatic PP Cell Fate Commitment Negative Regulation Of Retinoic Acid Biosynthetic Process Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Regulation Of Cell Development Regulation Of Neurogenesis Chromatin Organization Positive Regulation Of Cell Population Proliferation Phospholipase C Activator Activity	Protein-containing Complex Organization Ventral Spinal Cord Interneuron Fate Determination Type B Pancreatic Cell Fate Commitment DGTPase Activity DGTP Binding Triphosphoric Monoester Hydrolase Activity Deoxynucleoside Triphosphate Hydrolase Activity Positive Regulation Of Translational Fidelity TRNA-2-methylthio-N(6)-dimethylallyladenosine(37) Synthase Activity