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ADGRE5 and CD55
Number of citations of the paper that reports this interaction (PubMedID
10540231
)
26
Data Source:
HPRD
(in vivo)
ADGRE5
CD55
Description
adhesion G protein-coupled receptor E5
CD55 molecule (Cromer blood group)
Image
GO Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Focal Adhesion
Membrane
Secretory Granule Membrane
Extracellular Exosome
Golgi Membrane
Extracellular Region
Plasma Membrane
Cell Surface
Membrane
Transport Vesicle
Secretory Granule Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Membrane Raft
Extracellular Exosome
Side Of Membrane
Ficolin-1-rich Granule Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
G Protein-coupled Receptor Activity
Calcium Ion Binding
Protein Binding
Virus Receptor Activity
Protein Binding
Lipid Binding
Biological Process
Immune System Process
Inflammatory Response
Immune Response
Cell Adhesion
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Immune System Process
Regulation Of Lymphocyte Mediated Immunity
Positive Regulation Of T Cell Cytokine Production
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Complement Activation, Classical Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Complement Activation
Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Innate Immune Response
Respiratory Burst
Negative Regulation Of Complement Activation
Symbiont Entry Into Host Cell
Regulation Of Complement-dependent Cytotoxicity
Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways
Class B/2 (Secretin family receptors)
Neutrophil degranulation
Class B/2 (Secretin family receptors)
Neutrophil degranulation
COPI-mediated anterograde transport
Regulation of Complement cascade
Drugs
Chloramphenicol
Diseases
Complement regulatory protein defects, including the following six diseases: C1 inhibitor deficiency (hereditary angioedema); C4 binding protein alpha deficiency; C4 binding protein beta deficiency; Factor I deficiency; Decay-accelerating factor (CD55) deficiency; CD59 deficiency
GWAS
Refractive error (
32231278
)
Spherical equivalent (joint analysis main effects and education interaction) (
27020472
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
3 interacting genes:
CD55
HNRNPD
XRN1
6 interacting genes:
ADGRE5
CD14
CR1
FYN
GPLD1
LCK
Entrez ID
976
1604
HPRD ID
03130
00500
Ensembl ID
ENSG00000123146
ENSG00000196352
Uniprot IDs
P48960
B1AP13
P08174
PDB IDs
2BOU
7DO4
7YDH
7YDJ
7YDM
7YDP
8IKJ
8IKL
1H03
1H04
1H2P
1H2Q
1M11
1NWV
1OJV
1OJW
1OJY
1OK1
1OK2
1OK3
1OK9
1UOT
1UPN
2C8I
2QZD
2QZF
2QZH
3IYP
3J24
5FOA
6ILJ
6ILK
6LA5
7C9W
7DO4
7VY5
7VY6
8B8R
8K9R
8K9T
Enriched GO Terms of Interacting Partners
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Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Hepatocyte Dedifferentiation
Regulation Of Telomere Maintenance
Cellular Response To Putrescine
Regulation Of DNA Biosynthetic Process
Cellular Response To Puromycin
Cellular Response To Cycloheximide
Circadian Regulation Of Translation
Response To Rapamycin
RNA Catabolic Process
Positive Regulation Of Telomere Capping
Cell Dedifferentiation
MCRD-mediated MRNA Stability Complex
Response To Ketone
Regulation Of Chromosome Organization
Response To Alcohol
Response To Cycloheximide
5'-3' RNA Exonuclease Activity
G-quadruplex RNA Binding
Golgi Trans Cisterna
Response To Sodium Phosphate
Minor Groove Of Adenine-thymine-rich DNA Binding
G-quadruplex DNA Binding
Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Nucleobase-containing Compound Catabolic Process
CRD-mediated MRNA Stabilization
5'-3' Exonuclease Activity
Nuclear MRNA Surveillance
Regulation Of Complement-dependent Cytotoxicity
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Negative Regulation Of Complement Activation
Regulation Of Telomere Capping
Regulation Of Translation
Histone MRNA Catabolic Process
Cellular Response To Nitric Oxide
RRNA Catabolic Process
Positive Regulation Of Cytoplasmic Translation
3'-UTR-mediated MRNA Destabilization
Cellular Response To Reactive Nitrogen Species
Regulation Of Complement Activation
Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Respiratory Burst
Positive Regulation Of Alpha-beta T Cell Proliferation
Regulation Of DNA Metabolic Process
Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Positive Regulation Of Telomere Maintenance Via Telomerase
Response To Salt
Response To Nitric Oxide
Response To Ether
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-activating Signaling Pathway
Immune Response-regulating Signaling Pathway
Activation Of Immune Response
CD8 Receptor Binding
Positive Regulation Of Immune Response
CD4 Receptor Binding
Secretory Granule Membrane
Phospholipase Activator Activity
T Cell Receptor Binding
Complement Receptor Mediated Signaling Pathway
Regulation Of Immune Response
Phosphatidylinositol 3-kinase Binding
ATP Transport
Positive Regulation Of Immune System Process
Immune System Process
Phospholipase Binding
Cell Surface Receptor Signaling Pathway
Membrane Raft
Adenine Nucleotide Transport
Purine Nucleotide Transport
Fc-gamma Receptor Signaling Pathway
Nucleotide Transport
Regulation Of Regulatory T Cell Differentiation
Non-membrane Spanning Protein Tyrosine Kinase Activity
Positive Regulation Of T Cell Activation
T Cell Costimulation
Positive Regulation Of Leukocyte Cell-cell Adhesion
Peptidyl-tyrosine Phosphorylation
Response To Xenobiotic Stimulus
Regulation Of Immune System Process
Fc Receptor Signaling Pathway
Positive Regulation Of Multicellular Organismal Process
Opsonin Receptor Activity
Complement Component C3b Receptor Activity
Positive Regulation Of Lymphocyte Activation
Immune Complex Clearance By Erythrocytes
Positive Regulation Of Cell-cell Adhesion
Complement Component C4b Receptor Activity
Negative Regulation Of Serine-type Endopeptidase Activity
Cellular Response To Glycine
Response To Singlet Oxygen
Positive Regulation Of Alkaline Phosphatase Activity
Glycosylphosphatidylinositol Phospholipase D Activity
FMN Transmembrane Transporter Activity
FAD Transmembrane Transporter Activity
FAD Transmembrane Transport
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Carbohydrate Derivative Transport
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Tagcloud (Difference)
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Tagcloud (Intersection)
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