ADGRE5

Name	adhesion G protein-coupled receptor E5
Structure
Novel Interactors	1 novel interactors: GCC1
Interactors	3 interactors: CD55 HNRNPD XRN1
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Focal Adhesion Membrane Secretory Granule Membrane Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Immune System Process Inflammatory Response Immune Response Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling
Pathways	Class B/2 (Secretin family receptors) Neutrophil degranulation
GWAS	No GWAS studies recorded
Entrez ID	976
HPRD ID	03130
Ensembl ID	ENSG00000123146
Uniprot IDs	P48960
PDB IDs	2BOU 7DO4 7YDH 7YDJ 7YDM 7YDP 8IKJ 8IKL
GO Terms Enriched among Interactors ?	Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Hepatocyte Dedifferentiation Regulation Of Telomere Maintenance Cellular Response To Putrescine Regulation Of DNA Biosynthetic Process Cellular Response To Puromycin Cellular Response To Cycloheximide Circadian Regulation Of Translation Response To Rapamycin RNA Catabolic Process Positive Regulation Of Telomere Capping Cell Dedifferentiation MCRD-mediated MRNA Stability Complex Response To Ketone Regulation Of Chromosome Organization Response To Alcohol Response To Cycloheximide 5'-3' RNA Exonuclease Activity G-quadruplex RNA Binding Golgi Trans Cisterna Response To Sodium Phosphate Minor Groove Of Adenine-thymine-rich DNA Binding G-quadruplex DNA Binding Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Nucleobase-containing Compound Catabolic Process CRD-mediated MRNA Stabilization 5'-3' Exonuclease Activity Nuclear MRNA Surveillance Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Complement Activation Regulation Of Telomere Capping Regulation Of Translation Histone MRNA Catabolic Process Cellular Response To Nitric Oxide RRNA Catabolic Process Positive Regulation Of Cytoplasmic Translation 3'-UTR-mediated MRNA Destabilization Cellular Response To Reactive Nitrogen Species Regulation Of Complement Activation Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Respiratory Burst Positive Regulation Of Alpha-beta T Cell Proliferation Regulation Of DNA Metabolic Process Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Telomere Maintenance Via Telomerase Response To Salt Response To Nitric Oxide Response To Ether