ZNF646 and C11orf30

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF646	C11orf30
Gene Name		zinc finger protein 646	chromosome 11 open reading frame 30
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Protein Homodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification
Pathways
Drugs
Diseases
GWAS			Allergic rhinitis ( 22036096) Atopic dermatitis ( 23042114 19349984) Crohn's disease ( 18587394 21102463) IgE grass sensitization ( 22036096)
Protein-Protein Interactions		6 interactors: C11orf30 MDFI NINL PRKG1 TRAF2 UBE2I	6 interactors: BRCA2 CBX1 DDIT3 HIST3H3 ZMYND11 ZNF646
Entrez ID		9726	56946
HPRD ID		15886	10544
Ensembl ID		ENSG00000167395	ENSG00000158636
Uniprot IDs		O15015	B7ZKU0 B7ZKU2 E9PMC9 Q17RM7 Q7Z589
PDB IDs			1UTU 1UZ3 2FMM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of SUMO Transferase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity Regulation Of Catalytic Activity Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Binding Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Relaxation Of Vascular Smooth Muscle Positive Regulation Of Protein Homodimerization Activity CGMP-mediated Signaling Relaxation Of Smooth Muscle Positive Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Platelet Aggregation Cellular Response To Nitric Oxide Regulation Of Immunoglobulin Secretion Response To Nitric Oxide Regulation Of Cell-cell Adhesion Organelle Organization Negative Regulation Of Smooth Muscle Contraction Regulation Of Platelet Aggregation Trophoblast Giant Cell Differentiation Negative Regulation Of Platelet Activation Cellular Response To Stress Positive Regulation Of Catalytic Activity Protein Homotrimerization Positive Regulation Of T Cell Cytokine Production Regulation Of Protein Homodimerization Activity Positive Regulation Of MAPK Cascade Response To Stress Cellular Response To Reactive Nitrogen Species Positive Regulation Of Protein Kinase Activity Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Negative Regulation Of Muscle Contraction Regulation Of Cell Activation Relaxation Of Muscle Positive Regulation Of Kinase Activity Cytoplasmic Sequestering Of Protein	Negative Regulation Of Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Regulation Of Transcription Involved In Anterior/posterior Axis Specification Negative Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Chromosome Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Replication Fork Protection Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process ER Overload Response Response To UV-C Negative Regulation Of Gene Expression Apoptotic Signaling Pathway MRNA Transcription From RNA Polymerase II Promoter DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Blood Vessel Maturation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress MRNA Transcription Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Myoblast Differentiation Inner Cell Mass Cell Proliferation Cellular Macromolecule Biosynthetic Process Oocyte Maturation Macromolecule Biosynthetic Process Blastocyst Growth Male Meiosis I Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Interleukin-8 Production Response To X-ray Negative Regulation Of JNK Cascade Centrosome Duplication Chromatin Modification Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Stress-activated MAPK Cascade
Tagcloud ?			adam9 aurka birc5 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 prdm14 qiagen salsa top2a traf4
Tagcloud (Difference) ?			adam9 aurka birc5 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 prdm14 qiagen salsa top2a traf4
Tagcloud (Intersection) ?