ZNF646 and EMSY

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZNF646	EMSY
Description		zinc finger protein 646	EMSY transcriptional repressor, BRCA2 interacting
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription DNA Damage Response
Pathways
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Parkinson's disease ( 28892059)	Allergic rhinitis ( 31361310) Asthma ( 29273806 31361310 31959851 34103634) Asthma (adult onset) ( 31036433) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Eczema ( 31361310) Eosinophil count ( 29403010) Eosinophilic esophagitis ( 34506852) Type 1 diabetes ( 34012112)
Interacting Genes		7 interacting genes: EMSY LEUTX MDFI NINL PRKG1 TRAF2 UBE2I	14 interacting genes: AIDA AKT1 BRCA2 CBX1 CLVS2 DDIT3 DISC1 GET3 H3-4 LIX1 PSMA1 ZMYND11 ZNF131 ZNF646
Entrez ID		9726	56946
HPRD ID		15886	10544
Ensembl ID		ENSG00000167395	ENSG00000158636
Uniprot IDs		O15015	Q7Z589
PDB IDs			1UTU 1UZ3 2FMM
Enriched GO Terms of Interacting Partners?		Regulation Of JNK Cascade	PERK-mediated Unfolded Protein Response
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