EMC2 and SH3BP5L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMC2	SH3BP5L
Description		ER membrane protein complex subunit 2	SH3 binding domain protein 5 like
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane EMC Complex	Cytoplasm
	Molecular Function	Protein Binding Membrane Insertase Activity	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Male-pattern baldness ( 27182965 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)	Lead levels ( 26025379)
Interacting Genes		8 interacting genes: CCDC33 EMC8 EMC9 IKZF3 PCDHB12 RHOU SH3BP5L SS18L2	9 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB14 RAB25 SUOX YWHAG
Entrez ID		9694	80851
HPRD ID		09657	13887
Ensembl ID		ENSG00000104412	ENSG00000175137
Uniprot IDs		Q15006	Q7L8J4 Q96MW4
PDB IDs		6WW7 6Y4L 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Protein Insertion Into ER Membrane Protein Insertion Into Membrane	Myosin V Binding Sulfite Oxidase Activity Extrinsic Component Of Endoplasmic Reticulum Membrane Fibroblast Growth Factor Receptor Signaling Pathway G Protein Activity Pseudopodium Membrane
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