SH3BP5L and EMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SH3BP5L	EMC2
Description		SH3 binding domain protein 5 like	ER membrane protein complex subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane EMC Complex
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Membrane Insertase Activity
	Biological Process	Intracellular Signal Transduction	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Lead levels ( 26025379)	Brain morphology (MOSTest) ( 32665545) Male-pattern baldness ( 27182965 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)
Interacting Genes		9 interacting genes: CEP57 EMC2 FAM161B NINL PLEKHA5 RAB14 RAB25 SUOX YWHAG	8 interacting genes: CCDC33 EMC8 EMC9 IKZF3 PCDHB12 RHOU SH3BP5L SS18L2
Entrez ID		80851	9694
HPRD ID		13887	09657
Ensembl ID		ENSG00000175137	ENSG00000104412
Uniprot IDs		Q7L8J4 Q96MW4	Q15006
PDB IDs			6WW7 6Y4L 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Myosin V Binding Sulfite Oxidase Activity Extrinsic Component Of Endoplasmic Reticulum Membrane Fibroblast Growth Factor Receptor Signaling Pathway G Protein Activity Pseudopodium Membrane	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Protein Insertion Into ER Membrane Protein Insertion Into Membrane
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