EMC2 and SS18L2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		EMC2	SS18L2
Name		ER membrane protein complex subunit 2	SS18 like 2
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane EMC Complex	None
	Molecular Function	Protein Binding Membrane Insertase Activity	Protein Binding
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	None
GWAS		Brain morphology (MOSTest) ( 32665545 ) Male-pattern baldness ( 27182965 28196072 ) Ossification of the posterior longitudinal ligament of the spine ( 25064007 )	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: PBRM1
Interacting Genes		8 interacting genes: CCDC33 EMC8 EMC9 IKZF3 PCDHB12 RHOU SH3BP5L SS18L2	6 interacting genes: EMC2 FBXO7 GNG3 LYPD6 MBD5 TMEM17
Entrez ID		9694	51188
HPRD ID		09657	09399
Ensembl ID		ENSG00000104412	ENSG00000008324
Uniprot IDs		Q15006	Q9UHA2
PDB IDs		6WW7 6Y4L 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V	Not available
GO Terms Enriched among Interactors		Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Protein Insertion Into ER Membrane Protein Insertion Into Membrane	Extrinsic Component Of Endoplasmic Reticulum Membrane Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Hippocampal Interneuron Differentiation Lewy Body Core Positive Regulation Of Growth Hormone Receptor Signaling Pathway