EMC2 and PCDHB12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMC2	PCDHB12
Description		ER membrane protein complex subunit 2	protocadherin beta 12
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane EMC Complex	Plasma Membrane Membrane
	Molecular Function	Protein Binding Membrane Insertase Activity	Calcium Ion Binding Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Nervous System Development
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Male-pattern baldness ( 27182965 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)	Refractive error ( 32231278)
Interacting Genes		8 interacting genes: CCDC33 EMC8 EMC9 IKZF3 PCDHB12 RHOU SH3BP5L SS18L2	8 interacting genes: BLZF1 CCDC172 COPS4 EMC2 H2BC17 KRT19 USH1C ZSCAN23
Entrez ID		9694	56124
HPRD ID		09657	06956
Ensembl ID		ENSG00000104412	ENSG00000120328
Uniprot IDs		Q15006	Q9Y5F1
PDB IDs		6WW7 6Y4L 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Protein Insertion Into ER Membrane Protein Insertion Into Membrane
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