SS18L2 and EMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SS18L2	EMC2
Description		SS18 like 2	ER membrane protein complex subunit 2
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane EMC Complex
	Molecular Function	Protein Binding	Protein Binding Membrane Insertase Activity
	Biological Process		Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Male-pattern baldness ( 27182965 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)
Interacting Genes		6 interacting genes: EMC2 FBXO7 GNG3 LYPD6 MBD5 TMEM17	8 interacting genes: CCDC33 EMC8 EMC9 IKZF3 PCDHB12 RHOU SH3BP5L SS18L2
Entrez ID		51188	9694
HPRD ID		09399	09657
Ensembl ID		ENSG00000008324	ENSG00000104412
Uniprot IDs		Q9UHA2	Q15006
PDB IDs			6WW7 6Y4L 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Extrinsic Component Of Endoplasmic Reticulum Membrane Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Hippocampal Interneuron Differentiation Lewy Body Core Positive Regulation Of Growth Hormone Receptor Signaling Pathway	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Protein Insertion Into ER Membrane Protein Insertion Into Membrane
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