CTR9 and TCEA1

Number of citations of the paper that reports this interaction (PMID 20178742)
58

Data Source:
BioGRID (pull down)

		CTR9	TCEA1
Gene Name		CTR9, Paf1/RNA polymerase II complex component	transcription elongation factor A (SII), 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cdc73/Paf1 Complex Nuclear Speck Transcriptionally Active Chromatin	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Core Binding Protein Binding SH2 Domain Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Transcription, DNA-templated JAK-STAT Cascade Histone Monoubiquitination Wnt Signaling Pathway Stem Cell Maintenance Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Interleukin-6-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Histone H3-K4 Trimethylation Positive Regulation Of Histone H3-K79 Methylation	DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Erythrocyte Differentiation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways			Nucleotide Excision Repair Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: BLK CNTNAP2 HIST1H1C KMT2A SMAD9 TCEA1	17 interactors: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61
Entrez ID		9646	6917
HPRD ID		06717	03252
Ensembl ID		ENSG00000198730	ENSG00000187735
Uniprot IDs		Q6PD62	B7Z4S1 P23193
PDB IDs			1TFI 3NDQ
Enriched GO Terms of Interacting Partners?		Organ Development Positive Regulation Of Cellular Response To Drug Hemopoiesis Immune System Development Superior Temporal Gyrus Development Regulation Of Histone H3-K14 Acetylation Regulation Of Cellular Response To Drug Clustering Of Voltage-gated Potassium Channels System Development Regulation Of Response To Drug Multicellular Organismal Development Nucleosome Positioning Mullerian Duct Regression Anatomical Structure Development Protein Localization To Juxtaparanode Region Of Axon Neuronal Ion Channel Clustering Positive Regulation Of Transcription, DNA-templated Histone H3-K4 Trimethylation Regulation Of Histone H3-K9 Acetylation Developmental Process Histone H4-K16 Acetylation Thalamus Development Positive Regulation Of Histone H3-K4 Methylation Vocalization Behavior Striatum Development Positive Regulation Of Macromolecule Biosynthetic Process Anatomical Structure Regression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone H3-K4 Methylation Subpallium Development Peptidyl-lysine Trimethylation	Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated MRNA Processing Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Histone H2B Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Cell Fate Commitment Involved In Formation Of Primary Germ Layer Positive Regulation Of Gene Expression MRNA Metabolic Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Endodermal Cell Differentiation RNA Processing Regulation Of Nitrogen Compound Metabolic Process Endoderm Formation Transcription Elongation From RNA Polymerase II Promoter Stem Cell Maintenance Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Myeloid Cell Differentiation Endoderm Development MRNA Polyadenylation Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Histone Ubiquitination RNA Polyadenylation Negative Regulation Of Cell Differentiation Stem Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Protein Monoubiquitination Regulation Of Histone Modification Wnt Signaling Pathway Formation Of Primary Germ Layer Positive Regulation Of Viral Transcription
Tagcloud ?		antiparallel assembling assembly binds biochemical conserved coordinated detailed diverse elongation embryonic heterodimer histone identity leo1 maintenance modifications nucleosome octamer paf1 paf1c posttranscriptional recognition reveals scaffold shed sheet subcomplex tightly	arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Difference) ?		antiparallel assembling assembly binds biochemical conserved coordinated detailed diverse elongation embryonic heterodimer histone identity leo1 maintenance modifications nucleosome octamer paf1 paf1c posttranscriptional recognition reveals scaffold shed sheet subcomplex tightly	arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Intersection) ?