RGS6 and STMN2

Number of citations of the paper that reports this interaction (PMID 12140291)
11

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RGS6	STMN2
Gene Name		regulator of G-protein signaling 6	stathmin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Heterotrimeric G-protein Complex Plasma Membrane	Cytoplasm Endosome Golgi Apparatus Membrane Lamellipodium Axon Growth Cone Vesicle Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Signal Transducer Activity GTPase Activator Activity Protein Binding Protein Domain Specific Binding	Protein Binding Tubulin Binding Calcium-dependent Protein Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Intracellular Signal Transduction Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity Positive Regulation Of Neuron Differentiation	Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Cellular Response To Nerve Growth Factor Stimulus
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS		C-reactive protein ( 21300955) Economic and political preferences (environmentalism) ( 22566634) Obesity (extreme) ( 21935397) Smoking cessation ( 20811658)	Creutzfeldt-Jakob disease ( 19081515)
Protein-Protein Interactions		4 interactors: DMAP1 DNMT1 GNB5 STMN2	17 interactors: CCDC85A CDK1 CEP70 EEF1A1 GPRASP1 GPRASP2 MAPK10 MAPK3 NGFR PRKACA RGS20 RGS6 SUMO1 TEX11 TFCP2 TRPC5 TXLNA
Entrez ID		9628	11075
HPRD ID		04871	09003
Ensembl ID		ENSG00000182732	ENSG00000104435
Uniprot IDs		B7Z2A0 B7Z2N1 B7Z7N5 P49758 Q2M3K2	E5RGX5 Q93045
PDB IDs		2ES0
Enriched GO Terms of Interacting Partners?		DNA Methylation DNA Modification Regulation Of Gene Expression, Epigenetic C-5 Methylation Of Cytosine Positive Regulation Of Microtubule Depolymerization Negative Regulation Of Voltage-gated Calcium Channel Activity Maintenance Of DNA Methylation Positive Regulation Of Organelle Organization Histone H2A Acetylation DNA Methylation On Cytosine Methylation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Microtubule Polymerization Positive Regulation Of Histone H3-K4 Methylation Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Histone Methylation Positive Regulation Of Protein Depolymerization Negative Regulation Of Cation Channel Activity Regulation Of Voltage-gated Calcium Channel Activity Chromatin Modification Regulation Of Histone H3-K4 Methylation Regulation Of Rhodopsin Mediated Signaling Pathway Cellular Response To Nerve Growth Factor Stimulus Regulation Of Microtubule Polymerization Positive Regulation Of Protein Complex Disassembly Rhodopsin Mediated Signaling Pathway Chromatin Organization Negative Regulation Of Microtubule Depolymerization Cellular Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone Methylation Positive Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H4 Acetylation Regulation Of Organelle Organization Regulation Of Histone Methylation Negative Regulation Of Transmembrane Transport Cellular Response To Amino Acid Stimulus Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Chromosome Organization DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Histone Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression, Epigenetic	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Nuclear Envelope Organization Neurotrophin Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Signal Transduction MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Growth Factor Stimulus Activation Of Protein Kinase Activity Regulation Of Signaling Response To Growth Factor Chemotaxis Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade G2/M Transition Of Mitotic Cell Cycle Stress-activated Protein Kinase Signaling Cascade Nucleus Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Axon Guidance Activation Of MAPK Activity Activation Of Innate Immune Response Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Epidermal Growth Factor Positive Regulation Of Protein Kinase Activity Positive Regulation Of Innate Immune Response Positive Regulation Of Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Catalytic Activity Response To Fibroblast Growth Factor Mitotic Nuclear Envelope Disassembly Axonogenesis Positive Regulation Of MAP Kinase Activity
Tagcloud ?		aberrations accelerated anthracene atm augmented carcinogen carcinogenic concurrent confirming countermeasure deficit dimethylbenza dmba ductal genotoxic glands interrogate mammary means mecs obtaining oncogenesis restore suppress suppressive underlie unsurprisingly utilize viable	bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript
Tagcloud (Difference) ?		aberrations accelerated anthracene atm augmented carcinogen carcinogenic concurrent confirming countermeasure deficit dimethylbenza dmba ductal genotoxic glands interrogate mammary means mecs obtaining oncogenesis restore suppress suppressive underlie unsurprisingly utilize viable	bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript
Tagcloud (Intersection) ?