ZNF587 and CSRNP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZNF587	CSRNP1
Description		zinc finger protein 587	cysteine and serine rich nuclear protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Apoptotic Process Post-embryonic Development Positive Regulation Of Transcription By RNA Polymerase II Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis Roof Of Mouth Development Face Morphogenesis
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)	Brain-derived neurotrophic factor levels ( 33345186) Chronic lymphocytic leukemia ( 26956414) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Platelet count ( 32888494) Plateletcrit ( 32888494) Social communication problems ( 24564958)
Interacting Genes		130 interacting genes: ADAMTSL4 AQP6 ASB15 ASB6 AXIN2 BEGAIN C17orf50 CARD10 CARD9 CCDC125 CCDC136 CCDC85B CEP44 CEP70 CHRDL2 CSRNP1 CYSRT1 DEF8 DHX57 EFEMP2 FCHSD2 FHL3 FHL5 FSD2 FST GOLGA2 GOLGA6L9 GOPC GSC2 HMBOX1 HOOK2 HOXA1 HSF2BP IGFBP6 IKBKG IKZF1 IKZF3 INSC ISY1-RAB43 KATNBL1 KCTD7 KPRP KRT31 KRT38 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-7 KRTAP5-9 LDOC1 LHX3 LIMS1 LMO3 LRP2BP LZTS1 MCCD1 MDFI MEOX2 MID2 MKRN3 MTUS2 MYF5 NBPF19 NDUFB7 NEK6 NKAPL NOTCH2NLA NR1D2 PBX2 PDE4DIP PLSCR1 PNMA2 PPARA PRDM14 PRICKLE4 PRPF31 RORB RUNDC3A SMAD9 SMYD5 SOX13 SPRED1 SPRY2 SPRY3 SSX2IP STX11 TBC1D26 TCF4 TENM4 TFIP11 TMCC2 TNS2 TRAF1 TRIB3 TRIM23 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSC1 TSGA10 TXK VPS52 VWC2 ZBTB43 ZBTB8A ZGPAT ZIM2 ZKSCAN8 ZNF286A ZNF330 ZNF417 ZNF547 ZNF774 ZNF829 ZNF837 ZRANB1	6 interacting genes: AQP1 PPP1CA PRPF18 TCEANC ZNF417 ZNF587
Entrez ID		84914	64651
HPRD ID		15864	07347
Ensembl ID		ENSG00000198466	ENSG00000144655
Uniprot IDs		Q96SQ5	Q96S65
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Zinc Ion Binding Protein Binding Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity	Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development U2-type Post-spliceosomal Complex Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Generation Of Catalytic Spliceosome For Second Transesterification Step Nitric Oxide Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cerebrospinal Fluid Secretion Renal Water Absorption Carbon Dioxide Transmembrane Transporter Activity Positive Regulation Of Saliva Secretion Glomerulus Vasculature Development Water Transmembrane Transporter Activity Cellular Response To Mercury Ion Transepithelial Water Transport Hydrogen Peroxide Transmembrane Transport Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Intracellularly CGMP-activated Cation Channel Activity Carbon Dioxide Transmembrane Transport Lipid Digestion Pancreatic Juice Secretion Positive Regulation Of Termination Of DNA-templated Transcription Glycogen Granule Positive Regulation Of Termination Of RNA Polymerase II Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Ankyrin-1 Complex Renal Water Transport Glycerol Transmembrane Transport Nucleus Intracellular Water Homeostasis Regulation Of Saliva Secretion RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process PTW/PP1 Phosphatase Complex Ammonium Channel Activity Polyol Transmembrane Transport Response To Mercury Ion Double-strand Break Repair Via Alternative Nonhomologous End Joining Ammonium Transmembrane Transport Cellular Response To Salt Stress Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Digestive System Process Epithelial Fluid Transport
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