TBX4 and TENT5A

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TBX4	TENT5A
Description		T-box transcription factor 4	terminal nucleotidyltransferase 5A
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity	RNA Binding Protein Binding Transferase Activity Nucleotidyltransferase Activity Poly(A) RNA Polymerase Activity
	Biological Process	Angiogenesis Cell Fate Specification Morphogenesis Of An Epithelium Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Lung Development Embryonic Limb Morphogenesis Limb Morphogenesis Embryonic Hindlimb Morphogenesis Positive Regulation Of DNA-templated Transcription Skeletal System Morphogenesis Embryonic Lung Development	Response To Bacterium Regulation Of Ossification Positive Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation MRNA Stabilization
Pathways
Drugs
Diseases		Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
GWAS		Brain volume in infants (cerebrospinal fluid) ( 28763065) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) Heel bone mineral density ( 30598549) Height ( 18391951 19893584 25429064 28552196 31562340 33713608) Hip bone size ( 31053729) Hip circumference adjusted for BMI ( 34021172) Intertrochanteric region size ( 31053729) Manganese levels ( 26025379) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Waist circumference adjusted for body mass index ( 28552196 34021172)	Appendicular lean mass ( 33097823)
Interacting Genes		1 interacting genes: TENT5A	32 interacting genes: ARID5A ATXN1 BAG6 BCCIP BHLHE40 CD93 COL4A2 DMRTB1 DYNC1H1 EGLN2 GLIS2 HDLBP HTRA1 HYPK KEAP1 KRTAP26-1 NR2F2 PSG3 RHOXF2 RIN3 RNF14 RNF44 ROR2 SNRPC SPINT1 TBX4 TENT5B TNS2 TOLLIP YPEL3 ZC3H10 ZFYVE9
Entrez ID		9496	55603
HPRD ID		03424	13311
Ensembl ID		ENSG00000121075	ENSG00000112773
Uniprot IDs		P57082	Q96IP4
PDB IDs			8EXE 8EXF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Ossification Nucleotidyltransferase Activity Negative Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Catabolic Process Negative Regulation Of RNA Catabolic Process Poly(A) RNA Polymerase Activity RNA Stabilization Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation MRNA Stabilization Regulation Of Ossification Regulation Of Osteoblast Differentiation Regulation Of MRNA Stability Regulation Of RNA Stability
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