FAM46A and RNF14

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		FAM46A	RNF14
Gene Name		family with sequence similarity 46, member A	ring finger protein 14
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Poly(A) RNA Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Androgen Receptor Binding
	Biological Process	Regulation Of Gene Expression Regulation Of Blood Coagulation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Protein Ubiquitination Androgen Receptor Signaling Pathway Response To Estradiol Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 22976474) Corneal structure ( 23291589) Height ( 20881960 23563607)
Protein-Protein Interactions		16 interactors: ATXN1 BAG6 BCCIP CD93 COL4A2 DYNC1H1 EGLN2 HDLBP HTRA1 KEAP1 NR2F2 PSG3 RNF14 SPINT1 TBX4 ZFYVE9	22 interactors: AR DACH1 ESR1 FAM46A HNF1A HNRNPA1 NCOA4 NR3C1 PHF7 TAGLN TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2U UBE2V1 UBE2W VDR
Entrez ID		55603	9604
HPRD ID		13311	05745
Ensembl ID		ENSG00000112773	ENSG00000013561
Uniprot IDs		Q96IP4	B7Z229 Q9UBS8
PDB IDs
Enriched GO Terms of Interacting Partners?		Embryo Development Placenta Blood Vessel Development Intracellular Receptor Signaling Pathway Blood Vessel Development Vasculature Development Lung Development Respiratory Tube Development Radial Pattern Formation Respiratory System Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription Involved In Lymphatic Endothelial Cell Fate Commitment Anatomical Structure Development Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cardiovascular System Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Transcription, DNA-templated Blood Vessel Morphogenesis Dentinogenesis Proteasomal Ubiquitin-independent Protein Catabolic Process Embryonic Placenta Development Response To Estradiol RNA Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Developmental Process Tissue Development In Utero Embryonic Development Neuroendocrine Cell Differentiation Tail-anchored Membrane Protein Insertion Into ER Membrane Epithelium Development	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Steroid Hormone Mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Innate Immune Response Response To Organic Substance Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Hormone-mediated Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Protein Monoubiquitination Cellular Protein Catabolic Process Mammary Gland Branching Involved In Pregnancy Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Catabolic Process Cellular Response To Organic Substance Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress ISG15-protein Conjugation Regulation Of DNA-templated Transcription In Response To Stress Mammary Gland Duct Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Lipid TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Protein Modification Process Cellular Response To Stress Developmental Process Involved In Reproduction MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		al355149 algorithm annotation array cisplatin dataset deregulated deregulation existing fluorouracil lnc lncrna lncrnas man1a2 mbl2 microdissected ncfans nodal noticed paclitaxel ppp2r4 reannotation reserve scc sprr2d stxbp5 tongue tumorigenic validate
Tagcloud (Difference) ?		al355149 algorithm annotation array cisplatin dataset deregulated deregulation existing fluorouracil lnc lncrna lncrnas man1a2 mbl2 microdissected ncfans nodal noticed paclitaxel ppp2r4 reannotation reserve scc sprr2d stxbp5 tongue tumorigenic validate
Tagcloud (Intersection) ?