TBX4

Description		T-box transcription factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity
	Biological Process	Angiogenesis Cell Fate Specification Morphogenesis Of An Epithelium Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Lung Development Embryonic Limb Morphogenesis Limb Morphogenesis Embryonic Hindlimb Morphogenesis Positive Regulation Of DNA-templated Transcription Skeletal System Morphogenesis Embryonic Lung Development
Pathways
Drugs
Diseases		Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
GWAS		Brain volume in infants (cerebrospinal fluid) ( 28763065) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) Heel bone mineral density ( 30598549) Height ( 18391951 19893584 25429064 28552196 31562340 33713608) Hip bone size ( 31053729) Hip circumference adjusted for BMI ( 34021172) Intertrochanteric region size ( 31053729) Manganese levels ( 26025379) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Waist circumference adjusted for body mass index ( 28552196 34021172)
Interacting Genes		1 interacting genes: TENT5A
Entrez ID		9496
HPRD ID		03424
Ensembl ID		ENSG00000121075
Uniprot IDs		P57082
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Ossification Nucleotidyltransferase Activity Negative Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Catabolic Process Negative Regulation Of RNA Catabolic Process Poly(A) RNA Polymerase Activity RNA Stabilization Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation MRNA Stabilization Regulation Of Ossification Regulation Of Osteoblast Differentiation Regulation Of MRNA Stability Regulation Of RNA Stability
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