KIF23 and ARF3

Number of citations of the paper that reports this interaction (PMID 10506747)
18

Data Source:
HPRD (two hybrid, in vitro)

		KIF23	ARF3
Gene Name		kinesin family member 23	ADP-ribosylation factor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion Midbody Intercellular Bridge Mitotic Spindle Centralspindlin Complex	Golgi Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	GTPase Activity GTP Binding
	Biological Process	Mitotic Spindle Elongation Mitotic Cell Cycle Mitotic Cytokinesis Cytokinesis Microtubule-based Movement Blood Coagulation Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Small Molecule Metabolic Process
Pathways		Mitotic Telophase/Cytokinesis MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic M Phase Adaptive Immune System	Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ACTA1 ARF3 PLK1 RACGAP1 USP8 YWHAB YWHAG YWHAQ	9 interactors: ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 KIF23 PICK1 SLC2A4
Entrez ID		9493	377
HPRD ID		05455	00056
Ensembl ID		ENSG00000137807	ENSG00000134287
Uniprot IDs		Q02241	B7ZB63 P61204
PDB IDs		3VHX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitotic Cytokinesis Small GTPase Mediated Signal Transduction Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Regulation Of Organelle Organization Cytokinesis Positive Regulation Of Organelle Organization Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Stimulus Mitotic Cell Cycle Process Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Mitotic Cell Cycle Regulation Of Protein Localization Membrane Organization Protein Localization Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Response To Stimulus Regulation Of Cellular Localization Cell Cycle Process Protein Targeting Cell Division Regulation Of Intracellular Transport Regulation Of Chromosome Segregation Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Cell Cycle Cellular Protein Localization Actomyosin Structure Organization Skeletal Muscle Fiber Adaptation Activation Of APC-Cdc20 Complex Activity G2/M Transition Of Mitotic Cell Cycle Protein Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Division Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Cell Death Regulation Of Establishment Of Protein Localization Polar Body Extrusion After Meiotic Divisions Cell Proliferation Positive Regulation Of Transport	Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Amylopectin Biosynthetic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Localization Vesicle-mediated Transport Mitotic Spindle Midzone Assembly Positive Regulation Of Protein Catabolic Process Mitotic Spindle Elongation DNA Methylation Involved In Embryo Development Glucose Import Dendritic Spine Maintenance Transport Spindle Midzone Assembly Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Toxin Metabolic Process Negative Regulation Of Actin Nucleation Long Term Synaptic Depression
Tagcloud ?		alveolar astrocyte causing challenges col6a3 comparisons counting cpg cut epigenetic gbm gdna germ glioblastoma htb k27 lox lymphocyte lymphocytic methylation methyltransferase modifications mscc multiforme pbk percentages possessed regard summarized	abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative
Tagcloud (Difference) ?		alveolar astrocyte causing challenges col6a3 comparisons counting cpg cut epigenetic gbm gdna germ glioblastoma htb k27 lox lymphocyte lymphocytic methylation methyltransferase modifications mscc multiforme pbk percentages possessed regard summarized	abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative
Tagcloud (Intersection) ?