CD34 and ATF5

Number of citations of the paper that reports this interaction (PMID 10373550)
21

Data Source:
BioGRID (two hybrid)

		CD34	ATF5
Gene Name		CD34 molecule	activating transcription factor 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosome Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Basal Plasma Membrane Apical Plasma Membrane Glomerular Endothelium Fenestra Intercellular Bridge Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Transcription Factor Binding Carbohydrate Binding Sulfate Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Corepressor Activity Protein Binding Heat Shock Protein Binding
	Biological Process	Tissue Homeostasis Endothelial Cell Proliferation Glomerular Filtration Endothelium Development Signal Transduction Regulation Of Blood Pressure Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Single Organismal Cell-cell Adhesion Hemopoiesis Negative Regulation Of Blood Coagulation Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-10 Production Mesangial Cell-matrix Adhesion Paracrine Signaling Positive Regulation Of Odontogenesis Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Angiogenesis Cell Motility Regulation Of Immune Response Leukocyte Migration Transdifferentiation Vascular Wound Healing Hematopoietic Stem Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Granulocyte Colony-stimulating Factor Production Extracellular Vesicular Exosome Assembly Glomerular Endothelium Development Stem Cell Proliferation Metanephric Glomerular Mesangial Cell Differentiation Negative Regulation Of Cellular Response To Heat Negative Regulation Of Cellular Response To Hypoxia Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Glial Cell Line-derived Neurotrophic Factor Secretion Negative Regulation Of Neuron Death Positive Regulation Of Vasculogenesis	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Circadian Rhythm Post-embryonic Development Olfactory Bulb Interneuron Development Multicellular Organism Growth Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23326517) Heart rate ( 23583979) Resting heart rate ( 20639392)
Protein-Protein Interactions		5 interactors: ATF5 CHST4 CREM CRKL PRKCD	12 interactors: ATXN1 CCND3 CD34 CDC34 CEBPA CEBPE CEBPG DISC1 EP300 GABBR1 GABBR2 GIT2
Entrez ID		947	22809
HPRD ID		00790	05906
Ensembl ID		ENSG00000174059	ENSG00000169136
Uniprot IDs		B4DG27 P28906 Q5JTA5	Q9Y2D1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Circadian Rhythm Interleukin-10 Production Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Filopodium Assembly Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Interleukin-12 Production Positive Regulation Of Ceramide Biosynthetic Process Olfactory Bulb Interneuron Development Regulation Of Ceramide Biosynthetic Process Rhythmic Process Positive Regulation Of Phospholipid Transport Negative Regulation Of Platelet Aggregation Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Metabolic Process Parathyroid Gland Development Protein Sulfation Positive Regulation Of Cellular Biosynthetic Process Olfactory Bulb Interneuron Differentiation Leukocyte Tethering Or Rolling Negative Regulation Of Astrocyte Differentiation Regulation Of Superoxide Anion Generation Regulation Of Platelet Aggregation Negative Regulation Of Platelet Activation Positive Regulation Of Protein Dephosphorylation Sulfation Neutrophil Activation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress N-acetylglucosamine Metabolic Process Positive Regulation Of Lipid Catabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Astrocyte Differentiation Negative Regulation Of Cellular Metabolic Process Response To Growth Factor Cellular Extravasation Regulation Of Platelet Activation Cellular Senescence Regulation Of MAPK Cascade Immune System Process Negative Regulation Of Glial Cell Differentiation Forebrain Neuron Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Olfactory Bulb Development B Cell Proliferation	Response To Stimulus Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Macrophage Differentiation Positive Regulation Of Gene Expression Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Gamma-aminobutyric Acid Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Regulation Of Cellular Response To Heat Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Hemopoiesis Organ Development Myeloid Cell Differentiation Lung Development Respiratory Tube Development Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated Immune System Development Immune System Process Respiratory System Development Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Histone H2B Acetylation Positive Regulation Of Glial Cell Line-derived Neurotrophic Factor Secretion Negative Regulation Of Cellular Response To Heat Extracellular Vesicular Exosome Assembly Positive Regulation Of Macromolecule Biosynthetic Process Leukocyte Differentiation Positive Regulation Of Cytokine Production Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cell-cell Signaling Regulation Of CAMP Biosynthetic Process Positive Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Cellular Response To Hypoxia Mesangial Cell-matrix Adhesion Positive Regulation Of Granulocyte Colony-stimulating Factor Production Regulation Of CAMP Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Macrophage Colony-stimulating Factor Production Vascular Wound Healing N-terminal Peptidyl-lysine Acetylation Myeloid Leukocyte Differentiation
Tagcloud ?		agvhd alive allogeneic allografting allotransplantation anc ards august cgvhd donors evaluable february follows grades gvhd hematological leukaphereses mismatched mononucleated pbpc reach recipient scored september siblings sickle transplant unrelated unsupported	1beta activate cascades ccaat consistently cooperated ebp ebps effector elusive enhancer initiates interacted knockout luciferase mimicked nemo nlk opposite potentiated proinflammatory propagates proteasome screen stabilization stabilize tak1 though triggered
Tagcloud (Difference) ?		agvhd alive allogeneic allografting allotransplantation anc ards august cgvhd donors evaluable february follows grades gvhd hematological leukaphereses mismatched mononucleated pbpc reach recipient scored september siblings sickle transplant unrelated unsupported	1beta activate cascades ccaat consistently cooperated ebp ebps effector elusive enhancer initiates interacted knockout luciferase mimicked nemo nlk opposite potentiated proinflammatory propagates proteasome screen stabilization stabilize tak1 though triggered
Tagcloud (Intersection) ?