CD34 and CHST4

Number of citations of the paper that reports this interaction (PubMedID 10330415)
86

Data Source:
HPRD (in vitro)

		CD34	CHST4
Description		CD34 molecule	carbohydrate sulfotransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosome Plasma Membrane External Side Of Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Glomerular Endothelium Fenestra Intercellular Bridge Perinuclear Region Of Cytoplasm Cell Periphery	Golgi Membrane Golgi Apparatus Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Carbohydrate Binding Sulfate Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	N-acetylglucosamine 6-O-sulfotransferase Activity Sulfotransferase Activity Transferase Activity
	Biological Process	Tissue Homeostasis Endothelial Cell Proliferation Glomerular Filtration Endothelium Development Cell Adhesion Cell-matrix Adhesion Signal Transduction Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Hemopoiesis Negative Regulation Of Interleukin-2 Production Mesangial Cell-matrix Adhesion Paracrine Signaling Positive Regulation Of Odontogenesis Positive Regulation Of Angiogenesis Cell Motility Leukocyte Migration Transdifferentiation Vascular Wound Healing Hematopoietic Stem Cell Proliferation Positive Regulation Of Granulocyte Colony-stimulating Factor Production Extracellular Exosome Assembly Glomerular Endothelium Development Stem Cell Proliferation Metanephric Glomerular Mesangial Cell Differentiation Cell-cell Adhesion Positive Regulation Of Vasculogenesis	Carbohydrate Metabolic Process N-acetylglucosamine Metabolic Process Protein Sulfation Sulfur Compound Metabolic Process Inflammatory Response Immune Response Cell Adhesion Cell-cell Signaling Protein O-linked Glycosylation Via N-acetyl-galactosamine Positive Regulation Of Leukocyte Tethering Or Rolling
Pathways			O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Age-related macular degeneration ( 23326517) Automobile speeding propensity ( 30643258) Drug experimentation measurement ( 30718321) Estimated glomerular filtration rate ( 31152163) Febrile seizures (MMR vaccine-related) ( 25344690) Femur bone mineral density x serum urate levels interaction ( 34046847) General risk tolerance (MTAG) ( 30643258) Heart rate ( 23583979) Keratoconus ( 33649486) Refractive error ( 32231278) Resting heart rate ( 20639392 27798624) RR interval (heart rate) ( 30679814) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		4 interacting genes: AGR2 CHST4 CRKL PRKCD	2 interacting genes: CD34 DCPS
Entrez ID		947	10164
HPRD ID		00790	07477
Ensembl ID		ENSG00000174059	ENSG00000140835
Uniprot IDs		P28906	Q8NCG5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cellular Localization Positive Regulation Of Protein Localization Positive Regulation Of Protein Localization To Membrane Cell Chemotaxis Helper T Cell Diapedesis Chordate Pharynx Development Cerebellar Neuron Development Regulation Of Protein Localization Regulation Of Protein Localization To Membrane Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell-substrate Adhesion Negative Regulation Of Filopodium Assembly Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Positive Regulation Of Phospholipid Scramblase Activity Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Deoxyribonuclease Activity Positive Regulation Of Endodeoxyribonuclease Activity Protein Kinase C Signaling Termination Of Signal Transduction Protein Sulfation Lung Goblet Cell Differentiation Positive Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Leukocyte Migration N-acetylglucosamine 6-O-sulfotransferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Diapedesis Immune Response-regulating Cell Surface Receptor Signaling Pathway Parathyroid Gland Development Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Body Fluid Levels Regulation Of Endodeoxyribonuclease Activity Regulation Of Phospholipid Catabolic Process Extrinsic Component Of Postsynaptic Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Defense Response Endolysosome Positive Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Chemotaxis Cellular Response To Hydroperoxide Locomotion Positive Regulation Of Glial Cell Migration Immune Response-activating Signaling Pathway Postsynaptic Specialization Assembly	Extracellular Exosome Assembly Metanephric Glomerular Mesangial Cell Differentiation Glomerular Endothelium Fenestra Mesangial Cell-matrix Adhesion 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Positive Regulation Of Granulocyte Colony-stimulating Factor Production Positive Regulation Of Macrophage Colony-stimulating Factor Production Transdifferentiation Sulfate Binding Pericyte Cell Differentiation Paracrine Signaling Glomerular Epithelium Development Glomerular Endothelium Development Positive Regulation Of Odontogenesis Regulation Of Macrophage Colony-stimulating Factor Production Vascular Wound Healing Glomerular Filtration Regulation Of Vasculogenesis Regulation Of Odontogenesis Endothelium Development Angiogenesis Involved In Wound Healing Positive Regulation Of Vasculogenesis Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA 7-methylguanosine Cap Binding Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Methylguanosine-cap Decapping RNA Exonuclease Activity MRNA Cis Splicing, Via Spliceosome Renal Filtration RNA Decapping Hematopoietic Stem Cell Proliferation Negative Regulation Of Interleukin-2 Production Cell Differentiation Involved In Kidney Development Endothelial Cell Proliferation Negative Regulation Of Gene Expression Regulation Of Interleukin-2 Production Basal Plasma Membrane Kidney Epithelium Development Stem Cell Proliferation Regulation Of Animal Organ Morphogenesis Cell Periphery Intercellular Bridge MRNA Destabilization P-body RNA Destabilization Cell-matrix Adhesion Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of MRNA Catabolic Process Renal System Process MRNA Catabolic Process
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