ATF5 and CEBPE

Number of citations of the paper that reports this interaction (PMID 23661758)
2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		ATF5	CEBPE
Gene Name		activating transcription factor 5	CCAAT/enhancer binding protein (C/EBP), epsilon
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Cytoplasm	Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Corepressor Activity Protein Binding Heat Shock Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Circadian Rhythm Post-embryonic Development Olfactory Bulb Interneuron Development Multicellular Organism Growth Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Nucleic Acid-templated Transcription	Transcription, DNA-templated Phagocytosis Defense Response Macrophage Differentiation Cytokine Biosynthetic Process Defense Response To Bacterium Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23512250 19684604)
Protein-Protein Interactions		12 interactors: ATXN1 CCND3 CD34 CDC34 CEBPA CEBPE CEBPG DISC1 EP300 GABBR1 GABBR2 GIT2	44 interactors: ALX4 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CCT7 CEBPA CEBPD CEBPG COPS3 CSNK1A1L DDIT3 DENND4A E2F1 EDA2R FOS FOSL1 GATA1 GPR22 GTF2A1L IL7 JUN KDM2B LDOC1 MED16 MLLT6 MYB NELFB PIAS1 POU2F1 PSAT1 RB1 SIPA1L1 SPI1 STAT6 TAF5L TBX2 TCEB2 UBE2I ZFP2 ZMYM2 ZNF384
Entrez ID		22809	1053
HPRD ID		05906	02852
Ensembl ID		ENSG00000169136	ENSG00000092067
Uniprot IDs		Q9Y2D1	Q15744
PDB IDs			3T92
Enriched GO Terms of Interacting Partners?		Response To Stimulus Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Macrophage Differentiation Positive Regulation Of Gene Expression Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Gamma-aminobutyric Acid Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Regulation Of Cellular Response To Heat Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Hemopoiesis Organ Development Myeloid Cell Differentiation Lung Development Respiratory Tube Development Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated Immune System Development Immune System Process Respiratory System Development Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Histone H2B Acetylation Positive Regulation Of Glial Cell Line-derived Neurotrophic Factor Secretion Negative Regulation Of Cellular Response To Heat Extracellular Vesicular Exosome Assembly Positive Regulation Of Macromolecule Biosynthetic Process Leukocyte Differentiation Positive Regulation Of Cytokine Production Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cell-cell Signaling Regulation Of CAMP Biosynthetic Process Positive Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Cellular Response To Hypoxia Mesangial Cell-matrix Adhesion Positive Regulation Of Granulocyte Colony-stimulating Factor Production Regulation Of CAMP Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Macrophage Colony-stimulating Factor Production Vascular Wound Healing N-terminal Peptidyl-lysine Acetylation Myeloid Leukocyte Differentiation	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Gene Expression Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Leukocyte Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Cellular Process Myeloid Cell Differentiation Hemopoiesis Myeloid Leukocyte Differentiation Cellular Metabolic Process Immune System Development Negative Regulation Of Cellular Metabolic Process Organ Development Dendritic Cell Differentiation Anatomical Structure Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity System Development Myeloid Dendritic Cell Differentiation Leukocyte Activation Myeloid Dendritic Cell Activation
Tagcloud ?		1beta activate cascades ccaat consistently cooperated ebp ebps effector elusive enhancer initiates interacted knockout luciferase mimicked nemo nlk opposite potentiated proinflammatory propagates proteasome screen stabilization stabilize tak1 though triggered	10months 12p absolutely aligned alive altogether apart arid5b associating bcp boy chance divergent etv6 girl gstm1 gstt1 haa ikzf1 leukocytosis microsatellite nqo1 predisposition ptprj relapsed runx1 sibs tp63 twinned
Tagcloud (Difference) ?		1beta activate cascades ccaat consistently cooperated ebp ebps effector elusive enhancer initiates interacted knockout luciferase mimicked nemo nlk opposite potentiated proinflammatory propagates proteasome screen stabilization stabilize tak1 though triggered	10months 12p absolutely aligned alive altogether apart arid5b associating bcp boy chance divergent etv6 girl gstm1 gstt1 haa ikzf1 leukocytosis microsatellite nqo1 predisposition ptprj relapsed runx1 sibs tp63 twinned
Tagcloud (Intersection) ?