ITM2A and CLDN7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ITM2A	CLDN7
Description		integral membrane protein 2A	claudin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Membrane	Plasma Membrane Bicellular Tight Junction Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane Anchoring Junction
	Molecular Function	Amyloid-beta Binding Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Plasma Cell Differentiation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Birth weight ( 31043758) Graves' disease ( 23612905) Height ( 18391951) Nose size ( 27182965) Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)	Birth weight ( 27680694 31043758) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		7 interacting genes: CLDN7 FCGR1A FNDC9 MEOX2 SIT1 TMED9 TRIM14	77 interacting genes: AIG1 ANKRD46 APOD AQP2 ASGR1 BCL2L2 BET1 BMP10 C3orf52 CD53 CD72 CLN6 CMTM5 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB561D2 CYB5B CYBC1 EDDM3B EMP3 EPCAM ERG28 ERMP1 FAXDC2 FXYD6 GIMAP5 GLP1R GPR37L1 HGD IGFBP5 ITM2A JAGN1 LAT LEPROTL1 LPAR3 LSMEM2 MAL MALL MS4A13 NDUFB11 NIPAL4 NKG7 OLFM4 PGAP2 PLN RHOXF2 RPRM RTP2 SCAMP4 SCARF1 SEC22B SERTM1 SLC38A7 SLC61A1 SYNE4 TJP1 TMEM100 TMEM11 TMEM128 TMEM140 TMEM147 TMEM44 TMEM60 TMEM97 TNF TRARG1 TSPAN33 UBIAD1 UNC93B1 UPK1B UPK2 VAMP3 VAMP5 VSTM1
Entrez ID		9452	1366
HPRD ID		02200	07633
Ensembl ID		ENSG00000078596	ENSG00000181885
Uniprot IDs		O43736	A0A384ME58 F5H496 O95471
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Plasma Membrane Localization Within Membrane Transmembrane Ascorbate Ferrireductase Activity
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