SYTL3 and OAZ2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYTL3	OAZ2
Description		synaptotagmin like 3	ornithine decarboxylase antizyme 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endomembrane System Membrane Exocytic Vesicle	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding Small GTPase Binding Neurexin Family Protein Binding	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Intracellular Protein Transport Exocytosis	Biogenic Amine Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Positive Regulation Of Protein Catabolic Process Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways			Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs
Diseases
GWAS		Lipoprotein (a) levels ( 26377243) Neuritic plaque ( 31497858) Peripheral artery disease (borderline) ( 31388106) Refractive error ( 32231278)	Aluminium levels ( 26025379) Neuroticism ( 29255261)
Interacting Genes		4 interacting genes: ANKRD11 NRXN1 OAZ2 RAB27A	5 interacting genes: BDKRB1 CDR2 OAZ1 ODC1 SYTL3
Entrez ID		94120	4947
HPRD ID		15462	11966
Ensembl ID		ENSG00000164674	ENSG00000180304
Uniprot IDs		B4E2A9 Q4VX76	O95190
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation Vesicle Localization Protein Complex Involved In Cell-cell Adhesion Guanylate Kinase-associated Protein Clustering Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Complement-dependent Cytotoxicity Positive Regulation Of Neuromuscular Synaptic Transmission Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Exosomal Secretion Weibel-Palade Body Negative Regulation Of Filopodium Assembly Cerebellar Granule Cell Differentiation Postsynaptic Density Protein 95 Clustering Neuronal Signal Transduction NMDA Selective Glutamate Receptor Signaling Pathway NMDA Glutamate Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Trans-synaptic Protein Complex Gephyrin Clustering Involved In Postsynaptic Density Assembly AMPA Selective Glutamate Receptor Signaling Pathway Neuroligin Family Protein Binding Type 1 Fibroblast Growth Factor Receptor Binding Viral Translational Frameshifting Natural Killer Cell Degranulation Postsynaptic Membrane Assembly Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Vocal Learning Positive Regulation Of Synapse Maturation Postsynaptic Membrane Organization Presynaptic Membrane Assembly Observational Learning Presynaptic Membrane Organization Head Morphogenesis Synaptic Vesicle Clustering Secretion By Cell Acetylcholine Receptor Binding Neurotransmitter-gated Ion Channel Clustering Polyamine Biosynthetic Process Auditory Behavior Myosin V Binding Neuron Cell-cell Adhesion Glutamatergic Neuron Differentiation Mechanosensory Behavior	Polyamine Biosynthetic Process Polyamine Metabolic Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Biogenic Amine Metabolic Process Amine Metabolic Process Bradykinin Receptor Activity Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Ornithine Decarboxylase Activity Putrescine Biosynthetic Process From Arginine, Via Ornithine Signal Peptidase Complex Putrescine Biosynthetic Process Viral Translational Frameshifting Putrescine Metabolic Process Signal Peptide Processing Neurexin Family Protein Binding
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