SYTL3 and ANKRD11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYTL3	ANKRD11
Description		synaptotagmin like 3	ankyrin repeat domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endomembrane System Membrane Exocytic Vesicle	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding Small GTPase Binding Neurexin Family Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis	Odontogenesis Of Dentin-containing Tooth Skeletal System Morphogenesis Head Morphogenesis Face Development Face Morphogenesis
Pathways
Drugs
Diseases
GWAS		Lipoprotein (a) levels ( 26377243) Neuritic plaque ( 31497858) Peripheral artery disease (borderline) ( 31388106) Refractive error ( 32231278)	Eosinophil count ( 32888494) Femur bone mineral density x serum urate levels interaction ( 34046847) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 27863252 32888494) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: ANKRD11 NRXN1 OAZ2 RAB27A	92 interacting genes: ABHD11 AGR2 ANKRD33 ARID3A ARID5A BRCC3 C18orf54 C1QTNF2 CALCA CCDC196 CCHCR1 CCN3 CDC23 CDCA7L CDR2L CEP44 CFAP68 COG4 DEPTOR FAM136A FAM221B FOLR3 FTO GOLGA2 GOLGA6L9 GPRASP3 GRIPAP1 HAUS3 HDAC3 HDAC4 HDAC5 HOMEZ HOOK2 HRAS IGFBP6 IKZF1 ITGB3BP KANK2 KRT34 LZTS2 MECOM MKRN3 MTFR1L MTUS2 MXRA8 MYF5 NAB2 NCOA1 NCOA2 NCOA3 NOTO NTAQ1 PDE4DIP PIH1D2 PLAGL2 PPARA RAC3 RCOR3 RINT1 RPH3AL RSPO4 RUBCN SERTAD3 SNRNP35 SPANXN2 SPATA2 SPMIP5 SPRY1 SRC STMN3 STRA8 SYTL3 TADA2B TFIP11 TLE5 TNNI1 TRAF2 TRIM37 TRIM54 TSPOAP1 TTC23L TXN UFC1 USH1G USP54 USP6 VDR VHL ZNF426 ZNF552 ZNF655 ZNF688
Entrez ID		94120	29123
HPRD ID		15462	12456
Ensembl ID		ENSG00000164674	ENSG00000167522
Uniprot IDs		B4E2A9 Q4VX76	Q6UB99
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation Vesicle Localization Protein Complex Involved In Cell-cell Adhesion Guanylate Kinase-associated Protein Clustering Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Complement-dependent Cytotoxicity Positive Regulation Of Neuromuscular Synaptic Transmission Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Exosomal Secretion Weibel-Palade Body Negative Regulation Of Filopodium Assembly Cerebellar Granule Cell Differentiation Postsynaptic Density Protein 95 Clustering Neuronal Signal Transduction NMDA Selective Glutamate Receptor Signaling Pathway NMDA Glutamate Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Trans-synaptic Protein Complex Gephyrin Clustering Involved In Postsynaptic Density Assembly AMPA Selective Glutamate Receptor Signaling Pathway Neuroligin Family Protein Binding Type 1 Fibroblast Growth Factor Receptor Binding Viral Translational Frameshifting Natural Killer Cell Degranulation Postsynaptic Membrane Assembly Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Vocal Learning Positive Regulation Of Synapse Maturation Postsynaptic Membrane Organization Presynaptic Membrane Assembly Observational Learning Presynaptic Membrane Organization Head Morphogenesis Synaptic Vesicle Clustering Secretion By Cell Acetylcholine Receptor Binding Neurotransmitter-gated Ion Channel Clustering Polyamine Biosynthetic Process Auditory Behavior Myosin V Binding Neuron Cell-cell Adhesion Glutamatergic Neuron Differentiation Mechanosensory Behavior	Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone Deacetylase Complex Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Myotube Differentiation Regulation Of Myotube Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Striated Muscle Cell Differentiation Histone Deacetylase Activity, Hydrolytic Mechanism Nuclear Receptor-mediated Signaling Pathway Regulation Of Transcription By RNA Polymerase II Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Muscle Cell Differentiation Protein Lysine Deacetylase Activity Cellular Response To Thyroglobulin Triiodothyronine Nuclear Retinoid X Receptor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Centrosome Cycle Histone Deacetylase Activity Vitamin D Receptor Signaling Pathway Regulation Of Muscle Cell Differentiation Protein Deubiquitination DNA-binding Transcription Activator Activity Response To Thyroglobulin Triiodothyronine Regulation Of Primary Metabolic Process Protein Modification By Small Protein Removal
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