PEX16 and DEXI

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PEX16	DEXI
Description		peroxisomal biogenesis factor 16	Dexi homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix Protein To Membrane Docking ER-dependent Peroxisome Organization Protein Import Into Peroxisome Membrane ER-dependent Peroxisome Localization
Pathways		Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296) SAPHO syndrome ( 33816493)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Alopecia areata ( 25608926) Asthma ( 29273806 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859 26482879) Eosinophilic esophagitis ( 29904099) Gut microbiota (beta diversity) ( 27723756) Primary biliary cholangitis ( 26394269) Type 1 diabetes ( 25751624)
Interacting Genes		35 interacting genes: AQP6 BDKRB2 BIK CD79A CLEC10A CREB3L1 CYB5R3 DEXI EBAG9 ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FKBP7 GPR152 KCNJ6 LEPROTL1 MMGT1 PDZK1IP1 PEX19 PEX3 PGRMC2 REEP4 SAR1A SLC10A1 SLC10A6 SLC18A1 SLC35H1 SLC71A2 TIMMDC1 TMX2 TNFRSF17 UBC ZDHHC15	7 interacting genes: BMP10 C3orf52 GOLM1 PEX16 SGTB TBCD UBQLN1
Entrez ID		9409	28955
HPRD ID		04526	16798
Ensembl ID		ENSG00000121680	ENSG00000182108
Uniprot IDs		E9PP98 Q9Y5Y5	O95424
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Bile Acid:sodium Symporter Activity Protein Import Into Peroxisome Membrane Protein Binding Serotonin Transport Adaptive Immune Response Organic Hydroxy Compound Transport Mitochondrial Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Bile Acid And Bile Salt Transport
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