DEXI and PEX16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DEXI	PEX16
Description		Dexi homolog	peroxisomal biogenesis factor 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix Protein To Membrane Docking ER-dependent Peroxisome Organization Protein Import Into Peroxisome Membrane ER-dependent Peroxisome Localization
Pathways			Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Alopecia areata ( 25608926) Asthma ( 29273806 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859 26482879) Eosinophilic esophagitis ( 29904099) Gut microbiota (beta diversity) ( 27723756) Primary biliary cholangitis ( 26394269) Type 1 diabetes ( 25751624)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296) SAPHO syndrome ( 33816493)
Interacting Genes		7 interacting genes: BMP10 C3orf52 GOLM1 PEX16 SGTB TBCD UBQLN1	35 interacting genes: AQP6 BDKRB2 BIK CD79A CLEC10A CREB3L1 CYB5R3 DEXI EBAG9 ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FKBP7 GPR152 KCNJ6 LEPROTL1 MMGT1 PDZK1IP1 PEX19 PEX3 PGRMC2 REEP4 SAR1A SLC10A1 SLC10A6 SLC18A1 SLC35H1 SLC71A2 TIMMDC1 TMX2 TNFRSF17 UBC ZDHHC15
Entrez ID		28955	9409
HPRD ID		16798	04526
Ensembl ID		ENSG00000182108	ENSG00000121680
Uniprot IDs		O95424	E9PP98 Q9Y5Y5
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Bile Acid:sodium Symporter Activity Protein Import Into Peroxisome Membrane Protein Binding Serotonin Transport Adaptive Immune Response Organic Hydroxy Compound Transport Mitochondrial Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Bile Acid And Bile Salt Transport
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