SLC16A7 and LEMD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC16A7	LEMD1
Description		solute carrier family 16 member 7	LEM domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Membrane
	Molecular Function	Pyruvate Secondary Active Transmembrane Transporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Secondary Active Monocarboxylate Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding Pyruvate Transmembrane Transporter Activity	Protein Binding
	Biological Process	Monocarboxylic Acid Transport Lactate Transmembrane Transport Plasma Membrane Lactate Transport Transmembrane Transport Transport Across Blood-brain Barrier Pyruvate Transmembrane Transport
Pathways		Proton-coupled monocarboxylate transport
Drugs		Pyruvic acid
Diseases
GWAS		Adventurousness ( 30643258) Calcium levels ( 25972035) General risk tolerance (MTAG) ( 30643258) Hematocrit ( 29403010) Kawasaki disease ( 33692975) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Takayasu arteritis ( 25604533)	Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Sleep (1/3-day periodicity) ( 33075057)
Interacting Genes		15 interacting genes: ACSL5 CDIPT COMT CPEB1 FXYD6 GPR25 HMOX1 IFITM3 LEMD1 SFXN1 SMAGP SNTA1 TIMM23 VAPA VTI1B	13 interacting genes: AQP6 BLCAP EBP ERMAP JAGN1 MEOX2 MGST3 REEP4 RETREG3 SCN3B SLC16A7 TMPPE ZDHHC15
Entrez ID		9194	93273
HPRD ID		06791	13983
Ensembl ID		ENSG00000118596	ENSG00000186007
Uniprot IDs		O60669	Q68G75
PDB IDs		7BP3
Enriched GO Terms of Interacting Partners?		Membrane	Endoplasmic Reticulum Organization Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum Pyruvate Secondary Active Transmembrane Transporter Activity Cholesterol-5,6-oxide Hydrolase Activity PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Secondary Active Monocarboxylate Transmembrane Transporter Activity C-8 Sterol Isomerase Activity Cholestenol Delta-isomerase Activity
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