SYAP1 and ZFPL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		SYAP1	ZFPL1
Description		synapse associated protein 1	zinc finger protein like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Axon Dendrite Growth Cone Presynaptic Membrane Cell Projection Perikaryon Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Golgi Apparatus Membrane
	Molecular Function	Protein Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Cell Differentiation Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus TORC2 Signaling Positive Regulation Of Fat Cell Differentiation Regulation Of Short-term Neuronal Synaptic Plasticity Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Protein Serine/threonine Kinase Activity Cellular Response To Insulin-like Growth Factor Stimulus	Regulation Of DNA-templated Transcription Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: ADIPOQ MIP OGT POT1 THRA TNFRSF10C ZFPL1	64 interacting genes: AHNAK2 AQP6 ATP5MF BIK BSND CD3E CGRRF1 CLEC10A CLEC7A CPLX4 CREB3L1 CYBRD1 EBP ELOVL4 ERGIC3 FAM209A FATE1 FKBP7 FKBP8 FNDC9 FRMD3 GORAB GPR42 HIBADH KASH5 KLRC1 LDLRAD1 LEUTX LIME1 LINC00839 MFF MGST3 MIP MRM3 MRPS18B MS4A3 MTERF3 PGRMC2 PLEKHO1 PVR RELL2 SCN3B SGMS2 SHISAL1 SLC10A6 SLC19A3 SLC71A2 SLC7A14 SMIM3 SSMEM1 STX1A STX2 STX4 SYAP1 SYT1 TEX29 TM4SF19 TMEM106C TMEM139 TMEM14B TMEM237 TMEM31 TMPRSS2 TSTD2
Entrez ID		94056	7542
HPRD ID		06733	15729
Ensembl ID		ENSG00000169895	ENSG00000162300
Uniprot IDs		Q96A49	O95159
PDB IDs		1X3A
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cold-induced Thermogenesis Regulation Of Cold-induced Thermogenesis Negative Regulation Of Cellular Component Organization Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of DNA Biosynthetic Process Regulation Of Lipid Metabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Gluconeogenesis Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Chromatin DNA Binding Regulation Of DNA Biosynthetic Process Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Programmed Cell Death Thyroid Hormone Receptor Signaling Pathway Female Courtship Behavior Macromolecule Biosynthetic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Hormone-mediated Signaling Pathway Positive Regulation Of Female Receptivity Response To Monosaccharide Positive Regulation Of Lipid Metabolic Process Response To Glucose Response To Nutrient Regulation Of Glucose Metabolic Process Protein O-acetylglucosaminyltransferase Activity Circadian Rhythm Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Response To Linoleic Acid Detection Of Oxidative Stress Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Receptor Binding Negative Regulation Of DNA Metabolic Process Positive Regulation Of CAMP-dependent Protein Kinase Activity Negative Regulation Of Cholesterol Import Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly Negative Regulation Of Nucleobase-containing Compound Metabolic Process Thyroid Hormone Binding	Membrane SNARE Binding Protein Binding SNARE Complex Endomembrane System Vesicle Docking Cornified Envelope Assembly Organelle Localization By Membrane Tethering Synaptic Vesicle Exocytosis Membrane Docking SNAP Receptor Activity
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