ZFPL1 and FKBP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFPL1	FKBP8
Description		zinc finger protein like 1	FKBP prolyl isomerase 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Golgi Apparatus Membrane	Mitochondrion Mitochondrial Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System Membrane Mitochondrial Membrane Protein-containing Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Calmodulin Binding Isomerase Activity Identical Protein Binding Protein Folding Chaperone Metal Ion Binding Disordered Domain Specific Binding
	Biological Process	Regulation Of DNA-templated Transcription Vesicle-mediated Transport	Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Signal Transduction Smoothened Signaling Pathway Dorsal/ventral Pattern Formation Regulation Of Gene Expression Dorsal/ventral Neural Tube Patterning Neural Tube Development BMP Signaling Pathway Regulation Of BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process Neuron Fate Specification Regulation Of Macromolecule Metabolic Process Protein Localization To Mitochondrion Regulation Of Mitophagy
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS			Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)
Interacting Genes		64 interacting genes: AHNAK2 AQP6 ATP5MF BIK BSND CD3E CGRRF1 CLEC10A CLEC7A CPLX4 CREB3L1 CYBRD1 EBP ELOVL4 ERGIC3 FAM209A FATE1 FKBP7 FKBP8 FNDC9 FRMD3 GORAB GPR42 HIBADH KASH5 KLRC1 LDLRAD1 LEUTX LIME1 LINC00839 MFF MGST3 MIP MRM3 MRPS18B MS4A3 MTERF3 PGRMC2 PLEKHO1 PVR RELL2 SCN3B SGMS2 SHISAL1 SLC10A6 SLC19A3 SLC71A2 SLC7A14 SMIM3 SSMEM1 STX1A STX2 STX4 SYAP1 SYT1 TEX29 TM4SF19 TMEM106C TMEM139 TMEM14B TMEM237 TMEM31 TMPRSS2 TSTD2	52 interacting genes: AQP6 ARHGEF5 ARL13B ATP13A2 BCL2 BCL2L1 BIK BNIPL CD79A CIDEB CLCN1 CXCR2 CYB561 CYBRD1 EBP EGFR ELOVL4 ERBB2 ERGIC3 FAM174A FGF14 GPR37 JAGN1 MAPK14 MTOR OGT PEX12 PLN PPP3CA PSMC1 PSMD2 RETREG3 RHBDD2 RHEB SCN3B SHANK3 SLC10A1 SLC10A6 SLC35A5 SLC35B1 SLC71A2 SMO TERF1 TMEM14B TMEM254 TMEM31 TMEM43 TMEM45B TMEM80 TMX1 VHL ZFPL1
Entrez ID		7542	23770
HPRD ID		15729	05327
Ensembl ID		ENSG00000162300	ENSG00000105701
Uniprot IDs		O95159	B2R8G6 Q14318
PDB IDs			2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?		Membrane SNARE Binding Protein Binding SNARE Complex Endomembrane System Vesicle Docking Cornified Envelope Assembly Organelle Localization By Membrane Tethering Synaptic Vesicle Exocytosis Membrane Docking SNAP Receptor Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Regulation Of Cellular Localization Mitochondrial Membrane Negative Regulation Of Catabolic Process Regulation Of Protein Localization Bcl-2 Family Protein Complex Protein Binding Transmembrane Transport Negative Regulation Of Autophagy Dendritic Cell Apoptotic Process Ascorbate Homeostasis Intracellular Signal Transduction Regulation Of Membrane Potential Transmembrane Monodehydroascorbate Reductase Activity Striated Muscle Cell Development Skeletal Muscle Fiber Development Bile Acid:sodium Symporter Activity Positive Regulation Of Growth Regulation Of Protein Catabolic Process BH3 Domain Binding Myotube Cell Development Regulation Of Establishment Of Protein Localization Muscle Cell Development Negative Regulation Of Calcium Ion Transmembrane Transport Intracellular Signaling Cassette Regulation Of TORC1 Signaling Channel Activity ERBB2-EGFR Signaling Pathway Cell Morphogenesis Autophagy Negative Regulation Of Dendritic Cell Apoptotic Process Positive Regulation Of Striated Muscle Cell Differentiation Oligodendrocyte Differentiation Monoatomic Ion Transport Regulation Of Myotube Differentiation Positive Regulation Of Establishment Of Protein Localization Negative Regulation Of Translational Initiation Pyrimidine Nucleotide-sugar Transmembrane Transport Regulation Of Growth Positive Regulation Of Translational Initiation Mononuclear Cell Proliferation Nucleotide-sugar Transmembrane Transport Negative Regulation Of Calcium Ion Transport Identical Protein Binding Proteasomal Protein Catabolic Process Proteasome Regulatory Particle, Base Subcomplex Proteasome Regulatory Particle Ciliary Membrane
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