PIGS and TXNDC17

		PIGS	TXNDC17
Description		phosphatidylinositol glycan anchor biosynthesis class S	thioredoxin domain containing 17
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Peroxidase Activity Protein Binding Protein-disulfide Reductase [NAD(P)H] Activity
	Biological Process	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis	Tumor Necrosis Factor-mediated Signaling Pathway Cellular Oxidant Detoxification
Pathways		Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS			LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		14 interacting genes: CPEB2 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP19-2 KRTAP2-3 KRTAP2-4 KRTAP6-3 KRTAP9-2 NBPF19 NOTCH2NLA TRIP6	9 interacting genes: AVP DYNLL1 EXOSC8 INCA1 INS OXT RUFY1 TINF2 TXNRD1
Entrez ID		94005	84817
HPRD ID		15135	11656
Ensembl ID		ENSG00000087111	ENSG00000129235
Uniprot IDs		Q8NBL9 Q96IR5 Q96S52	A0A140VJY7 Q9BRA2
PDB IDs		7W72 7WLD 8IMX 8IMY	1WOU
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament	Neurohypophyseal Hormone Activity Maternal Aggressive Behavior Regulation Of Female Receptivity Female Mating Behavior Aggressive Behavior Grooming Behavior Positive Regulation Of Secretion Hormone Activity Positive Regulation Of Secretion By Cell Maternal Behavior Parental Behavior Secretory Granule Mating Behavior Neuronal Dense Core Vesicle Neuropeptide Hormone Activity Positive Regulation Of Blood Pressure Reproductive Behavior Identical Protein Binding Response To Electrical Stimulus Regulation Of Secretion By Cell Regulation Of Secretion Social Behavior V1B Vasopressin Receptor Binding Positive Regulation Of Hindgut Contraction Oxytocin Receptor Binding NADPH Peroxidase Activity Positive Regulation Of Transport Regulation Of Amine Transport V1A Vasopressin Receptor Binding Regulation Of Transport Negative Regulation Of Glycogen Catabolic Process Regulation Of Hindgut Contraction Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Perinucleolar Chromocenter Positive Regulation Of Lipid Biosynthetic Process Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Penile Erection Positive Regulation Of Norepinephrine Secretion Positive Regulation Of Female Receptivity Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Positive Regulation Of Cell Growth Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Vessel Diameter Maintenance
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