ZFAND4 and TFAP2C

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ZFAND4	TFAP2C
Gene Name		zinc finger, AN1-type domain 4	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus
	Molecular Function	Zinc Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Dimerization Activity
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Trophectodermal Cell Differentiation Hair Follicle Development Keratinocyte Development Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell-cell Signaling Male Gonad Development Forebrain Neuron Fate Commitment Cerebral Cortex Development Germ-line Stem Cell Maintenance Somatic Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic Regulation Of Cell Proliferation Regulation Of Epidermis Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Sebaceous Gland Development Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: TFAP2C	10 interactors: CCNG1 CITED1 CITED2 CITED4 GPR22 IKBKB NR1I2 TP53 UBE2I ZFAND4
Entrez ID		93550	7022
HPRD ID		16494	03361
Ensembl ID		ENSG00000172671	ENSG00000087510
Uniprot IDs		Q5VVY6 Q86XD8	Q92754
PDB IDs
Enriched GO Terms of Interacting Partners?		Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Germ-line Stem Cell Maintenance Branch Elongation Involved In Mammary Gland Duct Branching Keratinocyte Development Sebaceous Gland Development Forebrain Neuron Fate Commitment Mammary Gland Epithelial Cell Proliferation Trophectodermal Cell Differentiation Branch Elongation Of An Epithelium Axis Elongation Blastocyst Formation Branching Involved In Mammary Gland Duct Morphogenesis Forebrain Neuron Differentiation Mammary Gland Duct Morphogenesis Regulation Of Epidermis Development Somatic Stem Cell Maintenance Forebrain Generation Of Neurons Neuron Fate Commitment Mammary Gland Morphogenesis Epithelial Cell Proliferation Keratinocyte Differentiation Hair Follicle Development Hair Cycle Process Mammary Gland Epithelium Development Blastocyst Development Hair Cycle Epidermal Cell Differentiation Developmental Growth Involved In Morphogenesis Stem Cell Maintenance Male Gonad Development Cerebral Cortex Development Gland Morphogenesis Mammary Gland Development Male Sex Differentiation Branching Morphogenesis Of An Epithelial Tube Pallium Development Epithelial Cell Development Regulation Of Gene Expression, Epigenetic Central Nervous System Neuron Differentiation Skin Development Gonad Development Development Of Primary Sexual Characteristics Morphogenesis Of A Branching Epithelium Stem Cell Development Morphogenesis Of A Branching Structure Epidermis Development Developmental Growth Telencephalon Development Sex Differentiation	Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Response To Hormone Negative Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Signal Transduction Negative Regulation Of Gene Expression Response To Estrogen Negative Regulation Of Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Regulation Of Transcription, DNA-templated Response To Lipid Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Drug Export Response To Interleukin-11 Positive Regulation Of SUMO Transferase Activity Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Pattern Specification Process Cellular Response To Hypoxia Regulation Of Metabolic Process Cellular Response To Decreased Oxygen Levels Embryonic Organ Development Transcription, DNA-templated Negative Regulation Of Macromitophagy
Tagcloud ?			achieved additionally basal biopsy breast cd44 chemotherapy cluster cores immunohistochemistry luminal mb mda neoadjuvant overexpression pathologic pcr plasmid predictive pretreatment receiving regulates repressed represses residual specimens stained tumors
Tagcloud (Difference) ?			achieved additionally basal biopsy breast cd44 chemotherapy cluster cores immunohistochemistry luminal mb mda neoadjuvant overexpression pathologic pcr plasmid predictive pretreatment receiving regulates repressed represses residual specimens stained tumors
Tagcloud (Intersection) ?