EFTUD2 and SNRNP40

Number of citations of the paper that reports this interaction (PMID 16723661)
44

Data Source:
BioGRID (two hybrid, two hybrid)

		EFTUD2	SNRNP40
Gene Name		elongation factor Tu GTP binding domain containing 2	small nuclear ribonucleoprotein 40kDa (U5)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Membrane Nuclear Speck Catalytic Step 2 Spliceosome	Nucleoplasm U5 SnRNP Small Nucleolar Ribonucleoprotein Complex Cytoplasm Catalytic Step 2 Spliceosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Alcohol dependence ( 23455491)
Protein-Protein Interactions		16 interactors: ARPC3 CYFIP1 GOLM1 GSK3B HINFP HSPB1 LSM8 PIN1 PRPF6 PRPF8 SF1 SF3B3 SF3B4 SNRNP40 SREK1 WBP4	6 interactors: ACP5 APP DDR1 DHX16 EFTUD2 SNRNP200
Entrez ID		9343	9410
HPRD ID		04869	08481
Ensembl ID		ENSG00000108883	ENSG00000060688
Uniprot IDs		B3KX19 B4DMC0 K7EJ81 Q15029	A0MNP2 B4DQJ1 Q96DI7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Processing Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Positive Regulation Of Cellular Metabolic Process Spliceosomal Complex Assembly Ribonucleoprotein Complex Biogenesis Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Negative Regulation Of Phosphorylation Positive Regulation Of Organelle Organization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Gene Expression Regulation Of Organelle Organization Hypermethylation Of CpG Island Primary Sex Determination Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Cellular Biosynthetic Process MRNA 3'-splice Site Recognition Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Interleukin-3 Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Female Gonad Development Positive Regulation Of Metabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Neuron Maturation Axonogenesis Negative Regulation Of MAPK Cascade Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Microtubule Positive Regulation Of Actin Nucleation Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Protein Complex Assembly	MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Smooth Muscle Cell-matrix Adhesion Cis Assembly Of Pre-catalytic Spliceosome Negative Regulation Of Superoxide Anion Generation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Riboflavin Metabolic Process Axon Choice Point Recognition Heterocycle Metabolic Process Collagen-activated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Neuron Remodeling Smooth Muscle Cell Migration Regulation Of Extracellular Matrix Disassembly Regulation Of Superoxide Anion Generation Negative Regulation Of Interleukin-1 Beta Production Nitrogen Compound Metabolic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization RNA Metabolic Process Negative Regulation Of Reactive Oxygen Species Biosynthetic Process MRNA Cis Splicing, Via Spliceosome Cellular Copper Ion Homeostasis Negative Regulation Of Interleukin-12 Production Wound Healing, Spreading Of Cells Regulation Of Extracellular Matrix Organization Gene Expression Muscle Cell Migration Copper Ion Homeostasis Suckling Behavior Cellular Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Mammary Gland Lobule Development Mammary Gland Alveolus Development Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Branching Involved In Mammary Gland Duct Morphogenesis
Tagcloud ?		3k36me3 antagonizing arranged bromo bs69 called chromatin connects decorated depends h3k36me3 identifies intron ir modalities phd pwwp reader recognizes remarkably retention reveals snrnp spliceosome splicing tandemly trimethylation u5 zmynd11
Tagcloud (Difference) ?		3k36me3 antagonizing arranged bromo bs69 called chromatin connects decorated depends h3k36me3 identifies intron ir modalities phd pwwp reader recognizes remarkably retention reveals snrnp spliceosome splicing tandemly trimethylation u5 zmynd11
Tagcloud (Intersection) ?