ATP6V1F and CEP126

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP6V1F	CEP126
Description		ATPase H+ transporting V1 subunit F	centrosomal protein 126
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Endosome Membrane Membrane Vacuolar Proton-transporting V-type ATPase Complex Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Synapse Extracellular Exosome	Cytoplasm Centrosome Cytoskeleton Midbody Cell Projection Ciliary Base
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity ATPase-coupled Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Monoatomic Ion Transmembrane Transport Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport	Mitotic Spindle Organization Cell Projection Organization Cytoplasmic Microtubule Organization Cilium Assembly Non-motile Cilium Assembly
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		1 interacting genes: CEP126	87 interacting genes: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM200C FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MLH1 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RETREG2 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1 YWHAZ ZNF24
Entrez ID		9296	57562
HPRD ID		06198	17212
Ensembl ID		ENSG00000128524	ENSG00000110318
Uniprot IDs		A4D1K0 Q16864	Q9P2H0
PDB IDs		6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Non-motile Cilium Assembly Cytoplasmic Microtubule Organization Ciliary Base Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis Midbody Spindle Organization	Nucleus Organelle Organization Cytosol Histone H3-K14 Acetyltransferase Complex Protein Binding Establishment Of Organelle Localization Phosphoprotein Phosphatase Activity Microtubule Cytoskeleton Organization Involved In Mitosis Protein-RNA Complex Assembly DNA Replication-dependent Chromatin Disassembly Organelle Localization Cytoplasm Chromatin Binding Presynapse Axon Positive Regulation Of Aggrephagy Histone Acetyltransferase Complex DNA Repair Chromosome, Telomeric Region Regulation Of Circadian Rhythm Chromosome Organization
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