HIST3H2A and TCL1A

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HIST3H2A	TCL1A
Gene Name		histone cluster 3, H2a	T-cell leukemia/lymphoma 1A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Nucleosome Extracellular Vesicular Exosome	Endoplasmic Reticulum Cell Cortex Pronucleus
	Molecular Function	DNA Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	Nucleosome Disassembly UV-damage Excision Repair	Multicellular Organismal Development Stem Cell Maintenance
Pathways		Chromatin modifying enzymes HDACs deacetylate histones Chromatin organization HATs acetylate histones RMTs methylate histone arginines
Drugs
Diseases
GWAS			Adverse response to aromatase inhibitors ( 21172079 20876420)
Protein-Protein Interactions		5 interactors: CBX5 DNTTIP2 KRTAP10-3 RPS6KA5 TCL1A	21 interactors: AKT1 AKT2 AKT3 ALS2CR12 ATM CADPS CALCOCO2 CARD9 CEP55 DNMT3A GOLGA2 HIST3H2A LSM3 PRTFDC1 TCF4 TP53BP2 TRAF1 TTC33 TXLNA TXLNB WDR47
Entrez ID		92815	8115
HPRD ID		13660	01744
Ensembl ID		ENSG00000181218	ENSG00000100721
Uniprot IDs		Q7L7L0	P56279
PDB IDs			1JSG
Enriched GO Terms of Interacting Partners?		Histone H2A-S1 Phosphorylation Histone H3-S10 Phosphorylation Positive Regulation Of Histone Phosphorylation Histone H3-S28 Phosphorylation	Positive Regulation Of Glucose Metabolic Process Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Glycogen Metabolic Process Polysaccharide Metabolic Process Peripheral Nervous System Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Glial Cell Development Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Energy Reserve Metabolic Process Negative Regulation Of Lipid Transport Glucose Metabolic Process Glycogen Biosynthetic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Response To Radiation Glial Cell Differentiation Regulation Of Fatty Acid Transport Cell Cycle Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Intrinsic Apoptotic Signaling Pathway Cellular Polysaccharide Biosynthetic Process Regulation Of Glycogen Metabolic Process Schwann Cell Development Positive Regulation Of Glucose Transport Regulation Of Extrinsic Apoptotic Signaling Pathway Polysaccharide Biosynthetic Process Regulation Of Cell Cycle Hexose Metabolic Process Apoptotic Process Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Intracellular Transport Cellular Carbohydrate Metabolic Process Regulation Of Myelination Gliogenesis Programmed Cell Death Schwann Cell Differentiation Monosaccharide Metabolic Process Negative Regulation Of Transmembrane Transport Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Glycogen Cell Differentiation Involved In Embryonic Placenta Development Cell Death Regulation Of Glucose Import Death Regulation Of Lipid Catabolic Process Positive Regulation Of Lipid Biosynthetic Process
Tagcloud ?			14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Difference) ?			14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Intersection) ?