ODF4 and LAPTM4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ODF4	LAPTM4B
Description		outer dense fiber of sperm tails 4	lysosomal protein transmembrane 4 beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Endosome Membrane Endomembrane System Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle
	Molecular Function	Protein Binding	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Spermatogenesis Cell Differentiation	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 29403010)	Metabolite levels ( 23823483) QT interval ( 24952745)
Interacting Genes		22 interacting genes: APP CACNG1 CD9 CDIPT CNIH3 DEFB103A DEFB103B EBP LAPTM4B MARCHF5 MEOX2 MS4A13 NINJ2 RUSF1 SACM1L SLC25A46 SLC38A7 TMEM119 TMEM239 TOMM6 TRARG1 YIPF6	21 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM86B TRARG1
Entrez ID		146852	55353
HPRD ID		17658	13960
Ensembl ID		ENSG00000184650	ENSG00000104341
Uniprot IDs		C3TX97 Q2M2E3	Q86VI4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Chemoattractant Activity Positive Chemotaxis CCR6 Chemokine Receptor Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Defense Response To Gram-negative Bacterium	Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Transmembrane Transporter Activity Pyrimidine Nucleoside Transmembrane Transporter Activity Membrane Neurotransmitter Uptake Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Purine-containing Compound Transmembrane Transport Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Xenobiotic Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Quaternary Ammonium Group Transport Prostaglandin Transport Regulation Of Cell Growth Endosome To Plasma Membrane Protein Transport Transport Across Blood-brain Barrier Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Neurotransmitter Transport Dopamine Transport Neurotransmitter Reuptake Cellular Detoxification Xenobiotic Transmembrane Transporter Activity Monoamine Transport Regulation Of Growth Import Into Cell Plasma Membrane Positive Regulation Of Peptidyl-tyrosine Autophosphorylation Apical Plasma Membrane
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