KRTAP7-1 and RNF38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP7-1	RNF38
Description		keratin associated protein 7-1	ring finger protein 38
Image		No pdb structure
GO Annotations	Cellular Component	Intermediate Filament	Nucleus Nucleoplasm Sperm Flagellum
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Male Gonad Development Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS			Bipolar disorder (inflammation and infection response interaction) ( 25781172)
Interacting Genes		37 interacting genes: ARID5A C11orf16 C1orf94 CELF5 CREB5 CRYBA2 DTX2 FAM168A FOXH1 GATA2 GCM2 HGS HNRNPF MKRN3 MYOZ3 OTX1 PITX1 PITX2 PRR13 PSMB1 RANBP3 RHOXF2 RNF38 ROR2 SHARPIN SMARCC1 SNRPC SPAG8 TCF7L2 TEKT4 TFAP2D TLE5 TLX3 TOLLIP VPS37C YTHDF1 ZIC1	29 interacting genes: CYSRT1 DTX3 DZIP3 KPNA4 KPRP KRTAP10-8 KRTAP11-1 KRTAP19-5 KRTAP21-2 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 NEDD4 OXER1 RBM11 RNF114 RNF208 RUNX1 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2H UBE2N YAP1 ZDHHC17
Entrez ID		337878	152006
HPRD ID		19546	11519
Ensembl ID		ENSG00000274749	ENSG00000137075
Uniprot IDs		Q8IUC3	Q9H0F5
PDB IDs			1X4J 4V3K 4V3L 7OJX
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex Positive Regulation Of RNA Metabolic Process Chromatin Myoblast Fate Commitment Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Pituitary Gland Development Nucleus Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Embryonic Morphogenesis Gland Development GABAergic Neuron Differentiation DNA Binding Inner Ear Morphogenesis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Axonemal A Tubule Inner Sheath Nuclear Androgen Receptor Binding Ubiquitin Binding Protein Binding R-SMAD Binding Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Embryonic Hindlimb Morphogenesis Regulation Of Metabolic Process Diencephalon Morphogenesis Superior Vena Cava Morphogenesis Subthalamic Nucleus Development Multivesicular Body Assembly MRNA Splice Site Recognition Multivesicular Body Organization	Ubiquitin Conjugating Enzyme Activity Protein Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Intermediate Filament Ubiquitin Protein Ligase Activity Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein Modification Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cardiac Muscle Tissue Regeneration Proteolysis Protein K11-linked Ubiquitination Macromolecule Catabolic Process Transferase Activity Protein Monoubiquitination Protein Metabolic Process Protein Autoubiquitination Regulation Of Cellular Response To Growth Factor Stimulus Protein K63-linked Ubiquitination Catabolic Process Proline-rich Region Binding Positive Regulation Of Protein Polyubiquitination Protein Binding Protein K6-linked Ubiquitination
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