ZNF461 and TOX2

Number of citations of the paper that reports this interaction (PubMedID 14764631)
0

Data Source:
HPRD (two hybrid)

		ZNF461	TOX2
Description		zinc finger protein 461	TOX high mobility group box family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	DNA Binding Transcription Coactivator Activity Protein Binding Chromatin DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Colorectal cancer ( 30529582) Conduct disorder (symptom count) ( 20585324) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Red blood cell count ( 27863252 32888494) Refractive error ( 32231278) White blood cell count ( 32888494)
Interacting Genes		5 interacting genes: HDAC2 KRTAP10-3 MDFI SF1 TOX2	24 interacting genes: ANKS1A APP CENPP CSTF2T ENKD1 HCK HOMER3 HSF2BP HSFY1 HSFY2 LGALS4 MFHAS1 NDUFAB1 P4HA3 PHF1 RIBC1 SPG21 TCEA2 TEKT4 TEKT5 TLX3 UNC5CL YPEL3 ZNF461
Entrez ID		92283	84969
HPRD ID		16358	12734
Ensembl ID		ENSG00000197808	ENSG00000124191
Uniprot IDs		B4DRP8 Q8TAF7	H6UKR8 Q96NM4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Hair Follicle Placode Formation Regulation Of DNA-templated Transcription Histone Deacetylase Activity Negative Regulation Of RNA Metabolic Process Embryonic Morphogenesis Positive Regulation Of Male Mating Behavior Cellular Response To Dopamine Negative Regulation Of Transcription By Competitive Promoter Binding Eyelid Development In Camera-type Eye Sin3-type Complex Negative Regulation Of DNA-templated Transcription Response To Hyperoxia ESC/E(Z) Complex Regulation Of RNA Metabolic Process Response To Catecholamine Behavioral Response To Ethanol Deacetylase Activity Protein Decrotonylase Activity NuRD Complex Protein Lysine Deacetylase Activity Histone Decrotonylase Activity Progesterone Receptor Signaling Pathway Protein De-2-hydroxyisobutyrylase Activity Regulation Of RNA Biosynthetic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Protein Lysine Delactylase Activity Response To Dopamine Cellular Response To Catecholamine Stimulus Histone Deacetylase Activity, Hydrolytic Mechanism Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Fate Specification Response To Caffeine Negative Regulation Of Dendritic Spine Development Positive Regulation Of Oligodendrocyte Differentiation Fungiform Papilla Formation Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Cell Differentiation Involved In Embryonic Placenta Development U2AF Complex MRNA Cis Splicing, Via Spliceosome MRNA 3'-splice Site Recognition Cardiac Muscle Hypertrophy Negative Regulation Of Stem Cell Population Maintenance	Neuron Maturation Axonemal A Tubule Inner Sheath
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