TOX2 and ZNF461

Number of citations of the paper that reports this interaction (PMID 14764631)
3

Data Source:
HPRD (two hybrid)

		TOX2	ZNF461
Gene Name		TOX high mobility group box family member 2	zinc finger protein 461
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	DNA Binding Chromatin Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Conduct disorder (symptom count) ( 20585324)
Protein-Protein Interactions		2 interactors: APP ZNF461	4 interactors: HDAC2 KRTAP10-3 SF1 TOX2
Entrez ID		84969	92283
HPRD ID		12734	16358
Ensembl ID		ENSG00000124191	ENSG00000197808
Uniprot IDs		B4DQV8 Q96NM4	B4DRP8 Q8TAF7
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth	Chromatin Remodeling Maintenance Of Chromatin Silencing Primary Sex Determination Rhythmic Process MRNA 3'-splice Site Recognition Negative Regulation Of Female Gonad Development Negative Regulation Of MHC Class II Biosynthetic Process Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Transcription, DNA-templated RNA Biosynthetic Process Fungiform Papilla Morphogenesis Positive Regulation Of Receptor Biosynthetic Process Fungiform Papilla Development Regulation Of Sarcomere Organization Eyelid Development In Camera-type Eye Positive Regulation Of Male Gonad Development Regulation Of Female Gonad Development Hair Follicle Placode Formation Luteinization Positive Regulation Of Oligodendrocyte Differentiation Male Sex Determination Tongue Morphogenesis Chromatin Modification Maintenance Of Protein Location In Nucleus Negative Regulation Of Cardiac Muscle Tissue Development Regulation Of Receptor Biosynthetic Process Histone H4 Deacetylation Negative Regulation Of Cell Proliferation Leydig Cell Differentiation RNA Metabolic Process Chromatin Organization Sex Determination Gene Expression Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Collagen Metabolic Process Cellular Macromolecule Biosynthetic Process Histone H3 Deacetylation Macromolecule Biosynthetic Process Response To Organic Cyclic Compound Negative Regulation Of Organ Growth Tongue Development Positive Regulation Of Glial Cell Differentiation Chromatin Silencing Histone H3-K9 Modification Regulation Of Collagen Metabolic Process Regulation Of Oligodendrocyte Differentiation Regulation Of Cardiac Muscle Cell Proliferation Adrenal Gland Development Multicellular Organismal Aging
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